ある検診集団におけるPulse Wave Velosity, Ankle-Brachial Indexおよびhs-CRPレベルに関する臨床的検討

Atherosclerosis, especially, the pathogenesis of ischemic heart disease is exposed to attension the relations of chronic inflammations and it’s bio-maker. On the other hand, whether increased hs-CRP levels are also associated with PWV to indicate the development of symptomatic peripheral artery disease is unknown, and there are a few reports. In examination of 281 examples (age : 64.3±10.0) PWV, ABI and hs-CRP with other clinical test’s, such as BP, BMI, MBP, smoking and alcohol drinking rate, TC, HDL-C, TG, LDL-C were compared and estimated. As a results, PWV was positively related to BMI and there were depend on age and BP respectively, in constant, PWV and serum lipid levels was a little relevance. In hs-CRP positive group, obesity and smoking rate were high, and these indicated low-HDL-C nemia/hyper-TG nemia, furthermore the complication of ischemic heart disease were high frequency. Although there were not recognized a correlation with PWV and hs-CRP Accodingly, it is thought that PWV and hs-CRP in atherosclerosis separate from each clinical risk factors, and the findings of serum TC levels may be concerned with the secondary participations to these pathogenesis. Key words