直近一年間の累計
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ID 109917
タイトルヨミ
Trastuzumab/Capecitabine/Cisplatin HXP リョウホウ ニヨル 2ジ チリョウ ガ ユウコウ デアッタ シンコウ イガン ノ 1レイ
タイトル別表記
A case of the advanced gastric cancer of which second line chemotherapy using Trastuzumab/Capecitabine/Cisplatin therapy was effective
著者
湯浅, 康弘 徳島赤十字病院消化器外科
沖津, 宏 徳島赤十字病院消化器外科
枝川, 広志 徳島赤十字病院消化器外科
森, 理 徳島赤十字病院消化器外科
谷, 亮太朗 徳島赤十字病院消化器外科
蔵本, 俊輔 徳島赤十字病院消化器外科
松本, 大資 徳島赤十字病院消化器外科 KAKEN研究者をさがす
富林, 敦司 徳島赤十字病院消化器外科
キーワード
gastric cancer
second line chemotherapy
Trastuzumab
資料タイプ
学術雑誌論文
抄録
The case was a 69-year-old man, and gastric cancer (papillary adenocarcinoma) was diagnosed by a close inspection of the abdominal pain in 2008, and it was our department introduction. Show the type 0‐IIa+IIc like advanced lesion of gastric middle body gastrointestinal endoscope, and CT showed no regional lymph node and distant metastases, and we diagnosed it as c-T2 (MP), N0, M0, stageIB. We performed laparoscopic distal gastrectomy with D2 dissection, and in pathology, acknowledgment of severe lymph node metastases was obtained, and diagnosed it as T3 (SE), N2, M0, stageIIIB. We gave adjuvant chemotherapy with S-1and Cisplatin for 5 cycles, and maintenance S-1alone up to 24 months after surgery.
There was no recurrence for 39 months after surgery. But multiple metastases to lung recurrence was acknowledged and we performed S-1/Docetaxel therapy for 6 cycles, which lead to progressive disease. Then we performed Trastuzumab/Capecitabine/Cisplatin chemotherapy (HXP), the anti-tumor effect was good, and after 14 months later, showed a liver metastasis, but the tolerability was good. Generally, it is said that the chemotherapy is poor at an effect after the second line treatment, but HXP may be useful even in the second line chemotherapy.
掲載誌名
四国医学雑誌
ISSN
00373699
cat書誌ID
AN00102041
出版者
徳島医学会
71
1-2
開始ページ
29
終了ページ
34
並び順
29
発行日
2015-04-25
フルテキストファイル
言語
jpn
著者版フラグ
出版社版
部局
医学系