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ID 110416
タイトルヨミ
ゲンパツセイ コウジョウセンガン ノ ネンレイ ニヨル リンショウ ビョウリガクテキ トクチョウ オヨビ ヨゴ ノ ヒカク ケントウ
タイトル別表記
The impact of age on clinicopathologic features and prognosis of primary thyroid cancer
著者
紺谷, 桂一 香川大学医学部呼吸器・乳腺内分泌外科
森下, 敦司 高松赤十字病院胸部乳腺外科
久保, 尊子 高松赤十字病院胸部乳腺外科
橋本, 新一郎 香川大学医学部呼吸器・乳腺内分泌外科
村澤, 千沙 香川大学医学部呼吸器・乳腺内分泌外科
法村, 尚子 高松赤十字病院胸部乳腺外科
橋本, 希 香川大学医学部呼吸器・乳腺内分泌外科
監崎, 孝一郎 高松赤十字病院胸部乳腺外科
環, 正文 高松赤十字病院胸部乳腺外科
三浦, 一真 高松赤十字病院胸部乳腺外科
横見瀬, 裕保 香川大学医学部呼吸器・乳腺内分泌外科
キーワード
primary thyroid cancer
age
prognosis
資料タイプ
学術雑誌論文
抄録
Two-hundred thirty-six patients with primary thyroid cancer who received operation were divided into two groups by age, i.e.,59patients of age <45years(Early adulthood, EA)and177 patients of age≧45years(advanced age, AA). Clinicopathologic factors and disease-free survival (DFS)were compared between the two groups. There was no difference in clinicopathologic factors except for higher proportion of patients with poorly differentiated adenocarcinoma in the AA patients than in the EA patients(6.7% vs. 0%, p=0.041). DFS was significantly longer in the AA patients than in the EA patients(disease-free rates at10years after operation,94.8% vs. 72.5%, p=0.0031). Overall survival was not different between the two groups. The EA patients who showed shorten DFS were divided into two groups,17 patients of age <30 years (juvenile and young adult, JYA)and 42 patients of age ≧30 years, and DFS of each group was compared with that of the AA patients. Although disease-free survival rates at 10 years of the JYA patients were not different(92.6% vs.94.8%, p=0.125), those of patients of age ≧30years were significantly lower than those of the AA patients(70.0% vs. 94.8%, p=0.0021). These findings suggest that patients with primary thyroid cancer who are ≧30 years old in the young adulthood should be observed carefully after operation for early detection of relapse.
掲載誌名
四国医学雑誌
ISSN
00373699
cat書誌ID
AN00102041
出版者
徳島医学会
73
1-2
開始ページ
59
終了ページ
64
並び順
59
発行日
2017-04-25
フルテキストファイル
言語
jpn
著者版フラグ
出版社版