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ID 106141
タイトル別表記
FDG-PET/CTでの浸潤性膵管癌以外の膵腫瘍の悪性病変の検出能における視覚評価と標準摂取率での評価の比較検討
著者
音見, 暢一 徳島大学大学院医科学教育部(医学専攻) 徳島大学 教育研究者総覧 KAKEN研究者をさがす
Terazawa, Kaori The University of Tokushima
能勢, 隼人 The University of Tokushima
久保, 典子 The University of Tokushima
松崎, 健司 The University of Tokushima KAKEN研究者をさがす
キーワード
FDG
PET/CT
pancreatic lesion
資料タイプ
学位論文
抄録
Introduction The utility of FDG PET/CT for the detection and evaluation of invasive ductal carcinoma has been widely reported, but a few studies have assessed the utility of FDG PET/CT to detect malignancy in a variety of pancreatic lesions other than invasive ductal carcinoma. Purpose To compare the diagnostic performance of visual estimation with the semi-quantitative scores of FDG PET/CT for detecting malignancy in a variety of pancreatic lesions other than invasive ductal carcinoma. Material and Methods Images of pathologically proven pancreatic lesions from 32 patients were retrospectively evaluated : 14 benign lesions, 7 borderline (low malignant) lesions, and 11 malignant lesions. The average scores from visual estimation by the two observers were compared to two semi-quantiative analyses of FDG uptake in the lesions, namely the maximum standardized uptake value (SUVmax) and mean standardized uptake value (SUVmean). Results Visual analysis value, SUVmax and SUVmean were 0.33±0.21, 1.8±0.7 and 1.5±0.7 for the benign lesions, 0.70±0.28, 5.0±2.6 and 3.1±1.7 for the borderline lesions, and 0.73±0.18, 4.7±2.5 and 3.2±1.6 for the malignant lesions, respectively. Receiver operating characteristic analysis revealed the areas under the curves for detecting non-benign (malignant or borderline) lesions through visual analysis, SUVmax, and SUVmean were 0.914, 0.954, and 0.875, respectively. Conclusion For a variety of pancreatic lesions other than invasive ductal carcinoma, visual analysis and semi-quantitative analyses all showed strong diagnostic performance. However, semi-quantitative analysis with SUVmax proved to be the most effective method for detecting non-benign pancreatic lesions.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA12022913
AA11166929
出版者
Tokushima University Faculty of Medicine
61
1-2
開始ページ
171
終了ページ
179
並び順
171
発行日
2014-02
備考
内容要旨・審査要旨・論文本文の公開:
内容要旨・審査要旨 : LID201405131012.pdf
論文本文 : k2748_fulltext.pdf
本論文は,著者Yoichi Otomiの学位論文として提出され,学位審査・授与の対象となっている。
著者の申請により要約(2014-07-24公開)に替えて論文全文を公開(2019-12-19)
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
博士論文全文を含む
文科省報告番号
甲第2748号
学位記番号
甲医第1209号
学位授与年月日
2014-03-24
学位名
博士(医学)
学位授与機関
徳島大学
部局
病院
医学系