アクセス数 : ?
ダウンロード数 : ?
ID 111564
著者
Asanuma, Kotaro North Shore-Long Island Jewish Health System|North Shore University Hospital and New York University School of Medicine
Carbon-Correll, Maren North Shore-Long Island Jewish Health System|North Shore University Hospital and New York University School of Medicine
Eidelberg, David North Shore-Long Island Jewish Health System|North Shore University Hospital and New York University School of Medicine
キーワード
positron emission tomography (PET)
diffusion tensor imaging (DTI)
dystonia
network analysis
資料タイプ
学術雑誌論文
抄録
Functional neuroimaging, such as positron emission tomography(PET) and functional magnetic resonance imaging (fMRI), provides a valuable technique for detecting regional changes in brain metabolic activity associated with human disease. These techniques have been applied in different dystonic disorders including primary generalized dystonia and dopa-responsive dystonia (DRD), as well as focal dystonic syndromes such as torticollis, writer’s cramp, and blepharospasm. A common finding is abnormality of the basal ganglia and associated outflow pathways to sensorimotor cortex and other regions involved with motor performance. Other recent imaging research has utilized diffusion-based MRI techniques to localize distinct microstructural abnormalities in dystonia patients and gene carriers. This presentation will focus on an integrated approach to understanding the pathophysiology of this genetic and biochemically diverse disorder.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA11166929
AA12022913
出版者
Faculty of Medicine Tokushima University
52
Supplement
開始ページ
272
終了ページ
279
並び順
272
発行日
2005-11
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版