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ダウンロード数 : ?
ID 110828
著者
辻川, 哲也 Department of Radiology, Institute of Health Biosciences, The University of Tokushima Graduate School|Biomedical Imaging Research Center University of Fukui
野村, 昌弘 Faculty of Integrated Art and Sciences, Institute of Health Biosciences, The University of Tokushima Graduate School
中安, 紀美子 Faculty of Integrated Art and Sciences, Institute of Health Biosciences, The University of Tokushima Graduate School
河野, 智仁 Department of Digestive and Cardiovascular Medicine, Institute of Health Biosciences, The University of Tokushima Graduate School
中屋, 豊 Department of Nutrition and Metabolism, Institute of Health Biosciences, The University of Tokushima Graduate School 徳島大学 教育研究者総覧 KAKEN研究者をさがす
伊東, 進 Department of Digestive and Cardiovascular Medicine, Institute of Health Biosciences, The University of Tokushima Graduate School 徳島大学 教育研究者総覧
西谷, 弘 Department of Radiology, Institute of Health Biosciences, The University of Tokushima Graduate School 徳島大学 教育研究者総覧 KAKEN研究者をさがす
キーワード
acute coronary syndrome
MDCT
soft plaque
資料タイプ
学術雑誌論文
抄録
Purpose: The acute coronary syndrome is often caused by the rupture of plaques and thrombus formation even without significant stenosis, and patients with soft plaques, but without significant stenosis evidenced by coronary angiography(CAG), often develop an acute coronary syndrome. To address this discrepancy, a qualitative diagnosis of coronary plaques using a 16 slice multidetector-row CT was conducted.
Methods and Results: Volume rendering and cross-sectional MPR images were obtained. Based on the CT values, plaques on the coronary artery wall were classified as lipid-rich soft plaques(CT value<50 HU) and non-soft plaques (>50 HU) .
A significant correlation was observed between the percent stenosis determined in crosssectional MPR images and those determined by CAG(r=+0.92, p<0.01). Diffuse plaques with CT values of less than 50 HU often caused stenosis at level of 75% or less, which were not indicated by percutaneous transluminal coronary angioplasty.
Conclusions : Although diffuse soft plaques with CT values less than 50 HU are not an indication of intervention, a risk of an acute coronary syndrome exists, due to rupture. These soft plaques must be stabilized by treatment even when they do not cause significant stenosis, and MDCT is considered to be useful for their evaluation.
掲載誌名
The journal of medical investigation : JMI
ISSN
13431420
cat書誌ID
AA11166929
53
3-4
開始ページ
310
終了ページ
316
並び順
310
発行日
2006-08
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系