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ID 113267
タイトル別表記
亜急性期脳卒中患者および健常者における歩行観察時のミラーニューロンシステムの活性化
著者
日岡, 明美 徳島大学大学院医科学教育部(医学専攻)
Kitazato, Keiko Tokushima University
高麗, 雅章 Tokushima University
Akazawa, Naoki Tokushima Bunri University
キーワード
gait observation
mirror neuron system
stroke
fMRI
資料タイプ
学位論文
抄録
The observation of walking improves gait ability in chronic stroke survivors. It has also been suggested that activation of the mirror neuron system contributes to this effect. However, activation of the mirror neuron system during gait observation has not yet been assessed in sub-acute stroke patients. The objective of this study was to clarify the activation of mirror neuron system during gait observation in sub-acute stroke patients and healthy persons. In this study, we sequentially enrolled five sub-acute stroke patients who had undergone gait training and nine healthy persons. We used fMRI to detect neuronal activation during gait observation. During the observation period in the stroke group, neural activity in the left inferior parietal lobule, right and left inferior frontal gyrus was significantly higher than during the rest period. In the healthy group, neural activity in the left inferior parietal lobule, left inferior frontal gyrus, left middle frontal gyrus, left superior temporal lobule and right and left middle temporal gyrus was significantly higher than during the rest period. The results indicate that the mirror neuron system was activated during gait observation in sub-acute stroke patients who had undergone gait training and also in healthy persons. Our findings suggest that gait observation treatment may provide a promising therapeutic strategy in sub-acute stroke patients who have experienced gait training.
掲載誌名
Journal of Clinical Neuroscience
ISSN
09675868
cat書誌ID
AA10958444
出版者
Elsevier
60
開始ページ
79
終了ページ
83
発行日
2018-10-11
備考
内容要旨・審査要旨・論文本文の公開
本論文は, 著者Akemi Hiokaの学位論文として提出され, 学位審査・授与の対象となっている。
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
博士論文全文を含む
文科省報告番号
甲第3249号
学位記番号
甲医第1398号
学位授与年月日
2019-01-24
学位名
博士(医学)
学位授与機関
徳島大学
部局
医学系
病院