| ID | 114357 |
| タイトル別表記 | REARRANGEMENT OF c-myc GENE
|
| 著者 |
Shiraishi, Masahiko
National Cancer Center Research Institute
Hirohashi, Setsuo
National Cancer Center Research Institute
Morinaga, Shojiroh
National Cancer Center Research Institute
Shimosato, Yukio
National Cancer Center Research Institute
Sugimura, Takashi
National Cancer Center Research Institute
Sekiya, Takao
National Cancer Center Research Institute
|
| キーワード | c-myc
Rearrangement of gene
Giant cell carcinoma of the lung
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| 資料タイプ |
学術雑誌論文
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| 抄録 | The c-myc oncogene was found to be rearranged in a human cell line of giant cell carcinoma of the lung (C-Lu65) and in a human primary giant cell carcinoma of the lung (LuC38C). The rearrangements in C-Lu65 and LuC38C were in regions about 7.5kb and 6kb, respectively, upstream from the transcription initiation site. No rearrangement of the c-myc gene was observed in a non-cancerous portion (LuC38N) of the lung of the patient who carried LuC38C. These results suggest that rearrangement of the c-myc gene may play some role in tumorigenesis of giant cell carcinoma of the lung.
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| 掲載誌名 |
Japanese Journal of Cancer Research
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| ISSN | 09105050
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| cat書誌ID | AA00690844
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| 出版者 | Japanese Cancer Association
|
| 巻 | 77
|
| 号 | 8
|
| 開始ページ | 731
|
| 終了ページ | 735
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| 発行日 | 1986-08
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| EDB ID | |
| 出版社版DOI | |
| 出版社版URL | |
| フルテキストファイル | |
| 言語 |
eng
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| 著者版フラグ |
出版社版
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| 部局 |
歯学系
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