直近一年間の累計
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ID 117197
著者
土岐, 俊一 National Cancer Center|Tokushima University 徳島大学 教育研究者総覧
Sone, Miyuki National Cancer Center
Yoshida, Akihiko National Cancer Center
Gokita, Tabu Saitama Cancer Center
Kobayashi, Eisuke National Cancer Center
Nakatani, Fumihiko National Cancer Center
Chuman, Hirokazu National Cancer Center
Sugawara, Shunsuke National Cancer Center
Arai, Yasuaki National Cancer Center
Kawai, Akira National Cancer Center
資料タイプ
学術雑誌論文
抄録
Background: Image-guided percutaneous core needle biopsy (CNB) has been an important diagnostic procedure for musculoskeletal lesions. Here we surveyed the variety of diagnostic strategies available and assessed the clinical usefulness and limitations of image-guided CNB carried out by a multidisciplinary team comprising specialists in various fields.
Methods: We conducted a retrospective study of 284 image-guided CNBs among 1899 consecutive biopsy procedures carried out at our institution for musculoskeletal tumorous conditions, focusing on their effectiveness including diagnostic accuracy and utility for classification of specimens according to malignant potential and histological subtype as well as their correlation with biopsy routes.
Results: Among the 284 studied biopsies, 252 (88.7%) were considered clinically “effective”. The sensitivity for detection of malignancy was 94.0% (110/117) and the specificity was 95.3% (41/43). The diagnostic accuracy for detection of malignancy was 94.4% (151/160) and that for histological subtype was 92.3% (48/52). The clinical effectiveness of the procedure was correlated with the complexity of the biopsy route (P = 0.015); the trans-pedicular, trans-retroperitoneal and trans-sciatic foramen approaches tended to yield ineffective results. Repeat biopsy did not have a significant impact on the effectiveness of image-guided CNB (P = 0.536).
Conclusions: The diagnostic accuracy rates of image-guided CNB performed at multidisciplinary sarcoma units were usable even for patients who have variety of diagnostic biopsy procedures. It is important to establish and implement diagnostic strategies based on an understanding that complicated routes, especially for spine and pelvic lesions, may be associated with ineffectiveness and/or complications.
掲載誌名
Journal of Orthopaedic Science
ISSN
09492658
cat書誌ID
AA11052566
出版者
The Japanese Orthopaedic Association|Elsevier
27
2
開始ページ
448
終了ページ
455
発行日
2021-01-30
権利情報
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系