| ID | 116413 |
| 著者 |
板東, 浩
Tokushima University|Integrative Medicine Japan|Japan Low Carbohydrate Diet Promotion Association
KAKEN研究者をさがす
|
| キーワード | Glucagon-Like Peptide 1 (GLP-1)
GLP-1 receptor agonist (GLP-1RA)
blood brain barrier (BBB)
Semaglutide
weight reduction
|
| 資料タイプ |
学術雑誌論文
|
| 抄録 | For humans, eating control is crucial. When metabolic homeostasis can be maintained, feeding function involves the hypothalamus and brain stem. When food intake exceeds metabolic homeostasis, reward system is involved such as dopamine neurons from the ventral tegmental area, the nucleus accumbens, and limbic system and to the neocortex. Physiological effects of Glucagon-Like Peptide 1 (GLP-1) include improving glucose metabolism, delaying gastric emptying, and suppressing appetite. GLP-1 receptor agonist (GLP-1RA) is supposed to cross the blood brain barrier (BBB) and act on the central nervous system (CNS), associated with weight reduction effect, delaying gastric emptying via the vagus nerve system.
|
| 掲載誌名 |
Recent Research in Endocrinology and Metabolic Disorder
|
| ISSN | 27175138
|
| 巻 | 3
|
| 号 | 1
|
| 開始ページ | 40
|
| 終了ページ | 43
|
| 発行日 | 2021-10-25
|
| 権利情報 | This open access article is licensed under Creative Commons Attribution 4.0 International (CC BY 4.0). http://creativecommons.org/licenses/by/4.0
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| フルテキストファイル | |
| 言語 |
eng
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| 著者版フラグ |
出版社版
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| 部局 |
医学系
|
