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ID 117350
タイトル別表記
Prevalence of Exogenous Hormone Use in Japanese Women
著者
Ideno, Yuki Gunma University
Shinozaki, Hiromitsu Gunma University
Kitahara, Yoshikazu Gunma University
Nagai, Kazue Gunma University
Hayashi, Kunihiko Gunma University
キーワード
hormone replacement therapy
oral contraceptive
prevalence
nurse
資料タイプ
学術雑誌論文
抄録
Background: There have been few community-based epidemiological studies in which the prevalence of exogenous hormone use, including the use of oral contraceptives (OCs) and hormone replacement therapy (HRT), has been accurately assessed in Japan.
Methods: We have been conducting repeated surveys of participants in the Japan Nurses’ Health Study (JNHS), as a nationwide prospective cohort study, since 2001. We determined the prevalence of exogenous hormone use at baseline and during a 10-year follow-up period. A total of 15,019 female nurses participated in the JNHS follow-up cohort. We determined the prevalence of OC use in 14,839 women <60 years of age at baseline and the prevalence of HRT use in 7,915 women, excluding premenopausal women, at the last time they answered a questionnaire. The duration of HRT use was estimated using the Kaplan-Meier method.
Results: Six percent of the participants used OCs. The proportion of HRT users who stopped HRT before the baseline survey, the proportion of women using HRT during the follow-up period, and the proportion of all of the participants who had used HRT were 3.2%, 10.6%, and 13.8%, respectively. The median duration of HRT use was 2 years.
Conclusions: The lifetime prevalences of exogenous hormone use during this prospective study conducted in Japanese nurses were 6.0% for OCs and 13.8% for HRT. The information obtained in this study will be useful for clarification of the association between exogenous estrogen exposure and estrogen-related diseases as future research.
掲載誌名
Journal of Epidemiology
ISSN
13499092
09175040
cat書誌ID
AA10952696
出版者
Japan Epidemiological Association
32
3
開始ページ
117
終了ページ
124
発行日
2022-03-05
権利情報
This is an open access article distributed under the terms of Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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言語
eng
著者版フラグ
出版社版
部局
医学系