ID | 117350 |
タイトル別表記 | Prevalence of Exogenous Hormone Use in Japanese Women
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著者 |
Ideno, Yuki
Gunma University
Shinozaki, Hiromitsu
Gunma University
Kitahara, Yoshikazu
Gunma University
Nagai, Kazue
Gunma University
Hayashi, Kunihiko
Gunma University
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キーワード | hormone replacement therapy
oral contraceptive
prevalence
nurse
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資料タイプ |
学術雑誌論文
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抄録 | Background: There have been few community-based epidemiological studies in which the prevalence of exogenous hormone use, including the use of oral contraceptives (OCs) and hormone replacement therapy (HRT), has been accurately assessed in Japan.
Methods: We have been conducting repeated surveys of participants in the Japan Nurses’ Health Study (JNHS), as a nationwide prospective cohort study, since 2001. We determined the prevalence of exogenous hormone use at baseline and during a 10-year follow-up period. A total of 15,019 female nurses participated in the JNHS follow-up cohort. We determined the prevalence of OC use in 14,839 women <60 years of age at baseline and the prevalence of HRT use in 7,915 women, excluding premenopausal women, at the last time they answered a questionnaire. The duration of HRT use was estimated using the Kaplan-Meier method. Results: Six percent of the participants used OCs. The proportion of HRT users who stopped HRT before the baseline survey, the proportion of women using HRT during the follow-up period, and the proportion of all of the participants who had used HRT were 3.2%, 10.6%, and 13.8%, respectively. The median duration of HRT use was 2 years. Conclusions: The lifetime prevalences of exogenous hormone use during this prospective study conducted in Japanese nurses were 6.0% for OCs and 13.8% for HRT. The information obtained in this study will be useful for clarification of the association between exogenous estrogen exposure and estrogen-related diseases as future research. |
掲載誌名 |
Journal of Epidemiology
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ISSN | 13499092
09175040
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cat書誌ID | AA10952696
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出版者 | Japan Epidemiological Association
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巻 | 32
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号 | 3
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開始ページ | 117
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終了ページ | 124
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発行日 | 2022-03-05
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権利情報 | This is an open access article distributed under the terms of Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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言語 |
eng
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著者版フラグ |
出版社版
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部局 |
医学系
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