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ID 118038
著者
Kakiuchi, Naoya Tokushima University
Miyazaki, Aiko Tokushima University
Fujikawa, Akihiro Shikoku Riken
キーワード
Flow titration
flow ratiometry
triangular wave controlled
high throughput
vinegar
資料タイプ
学術雑誌論文
抄録
Unprecedented high throughput flow titration (maximally 43.1 titrations/min) has been realized by a triangular wave controlled flow ratiometry using an in-house LED-photodiode detector. The detector was fabricated mainly with quartz tubing, an LED, a photodiode and a DC power supply. While the total flow rate is held constant, a titrand (acid) is merged with a titrant (base) containing an indicator, the flow rate of which is linearly varied by the control voltage Vc supplied from a computer. Downstream, the intensity of the transmitted light is monitored with the detector and acquired in the computer as detector output voltage Vd. In the initial feedback-based mode, the lamp direction of Vc is changed from upward to downward, or vice versa, when the detector senses the equivalence point. In the subsequent fixed triangular wave controlled mode, the scan range and the scan rate of Vc are further limited and quickened, respectively, in order to increase the throughput rate. Equivalence point is determined by offsetting the effect of the lag time between the upstream merging and the downstream sensing. Although the present approach is an absolute method, calibration curves have been constructed for practical operation. The linearity of the curve is satisfactory (r2 › 0.993). The present method is well applicable to various titrations of acids and bases including acetic acid in commercial vinegars.
掲載誌名
FIA研究懇談会会誌
ISSN
0911775X
24337374
cat書誌ID
AA10962565
出版者
Japanese Association for Flow Injection Analysis
34
1
開始ページ
11
終了ページ
14
発行日
2017
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
薬学系