| ID | 115070 |
| 著者 |
Tsutsumi, Tomohiro
Tokushima University
Saitoh, Arisa
Tokushima University
Kasai, Tomoyo
Tokushima University
Chu, MengYue
Tokushima University
|
| キーワード | N,N-Dimethylaminopyridine
1,1,7,7-Tetramethyl-9-azajulolidine
Acylation catalyst
Quinolizidine alkaloid
Cascade reaction
|
| 資料タイプ |
学術雑誌論文
|
| 抄録 | 1,1,7,7-Tetramethyl-9-azajulolidine (TMAJ), which theoretical studies have suggested as a highly active DMAP analog, was synthesized for the first time. The catalytic activity of TMAJ was confirmed by the acetylation reactions of various tert-alcohols. TMAJ showed much higher catalytic activity than DMAP and one of the highest activity levels among the conventional DMAP analogs. These experimental results were in good agreement with the previous theoretical studies.
|
| 掲載誌名 |
Tetrahedron Letters
|
| ISSN | 00404039
|
| cat書誌ID | AA00861801
AA11539822
|
| 出版者 | Elsevier
|
| 巻 | 61
|
| 号 | 26
|
| 開始ページ | 152047
|
| 発行日 | 2020-05-17
|
| 権利情報 | © 2020. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
|
| EDB ID | |
| 出版社版DOI | |
| 出版社版URL | |
| フルテキストファイル | |
| 言語 |
eng
|
| 著者版フラグ |
著者版
|
| 部局 |
薬学系
|
