| ID | 113449 |
| 著者 |
Kiyama, Hiroki
Kyoto University
Kuroda, Yusuke
Kyoto University
Yamaoka, Yousuke
Kyoto University
Takasu, Kiyosei
Kyoto University
|
| キーワード | Optical resolution
Chiral alcohols
Chiral magnesium phosphate
Asymmetric addition
Imines
|
| 資料タイプ |
学術雑誌論文
|
| 抄録 | A new catalytic method for separating enantiomers of racemic compounds is proposed. Catalytic asymmetric addition of chiral trans-2-substituted cyclohexanols to imines provided diastereomeric mixtures of aminals, and the subsequent separation of the enantiomers by silicagel column chromatography and the hydrolysis of the aminals produced the alcohols in an optically active form.
|
| 掲載誌名 |
Tetrahedron Letters
|
| ISSN | 00404039
|
| cat書誌ID | AA00861801
AA11539822
|
| 出版者 | Elsevier
|
| 巻 | 60
|
| 号 | 2
|
| 開始ページ | 175
|
| 終了ページ | 177
|
| 発行日 | 2018-12-03
|
| 権利情報 | © 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
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| EDB ID | |
| 出版社版DOI | |
| 出版社版URL | |
| フルテキストファイル | |
| 言語 |
eng
|
| 著者版フラグ |
著者版
|
| 部局 |
薬学系
|
