直近一年間の累計
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ID 51880
タイトルヨミ
カンキョウ ホルモン ブッシツ ノ テイヨウリョウ エイキョウ オ カンガエル
著者
関澤, 純 徳島大学総合科学部自然システム物質科学
キーワード
endocrine disruptor
low-dose effect
neurobehavioral effect
bisphenol A
perinatal exposure
資料タイプ
学術雑誌論文
抄録
Low-dose effects of endocrine disruptors has raised much concern of both experts and general public. It is partly because the word “ Kankyo hormone”, used popularly in Japan as a synonym for endocrine disruptors without any scientific definition, misled people. However so called low-dose effects of the endocrine disruptors presented a new challenge to the basic notion of the threshold in toxicology, and the risk assessment of chemicals. Although hormonally active substances can potentially cause some effects at low doses, it should be addressed whether the effects are adverse to health and/or developmentally irreversible. Recently, a number of literatures reported that perinatal exposure to bisphenol A can cause neurobehavioral effects to rats and mice at low doses, which were not considered before. In this review, the author introduces new findings on low-dose effects from a research project supported by the Ministry of Health, Labor and Welfare, together with the outputs from international activities related to this subject.
掲載誌名
四国医学雑誌
ISSN
00373699
cat書誌ID
AN00102041
出版者
徳島医学会
62
3-4
開始ページ
113
終了ページ
119
並び順
113
発行日
2006-08-25
備考
EDB ID
フルテキストファイル
言語
jpn