| ID | 119290 |
| 著者 |
Ogasa, Chie
Tokushima University
Kayano, Kimika
Tokushima University
|
| キーワード | tert-butylation
amino acids
tert-butyl esters
tert-butyl ethers
bis(trifluoromethanesulfonyl)imide
tert-butylation reaction
free amino acid
tert-butyl ester
tert-butyl ether
|
| 資料タイプ |
学術雑誌論文
|
| 抄録 | A simple and safe tert-butylation reaction was developed. Treatment of various free amino acids with 1.1 equiv of bis(trifluoromethanesulfonyl)imide in tert-butyl acetate directly afforded tert-butyl esters with free amino groups quickly and in good yields. In addition, various carboxylic acids and alcohols without amino groups were converted to tert-butyl esters and ethers in high yields with small catalytic amounts of bis(trifluoromethanesulfonyl)imide. All tert-butylation reactions of free amino acids, carboxylic acids, and alcohols proceeded much faster and in high yields compared to conventional methods.
|
| 掲載誌名 |
Synlett
|
| ISSN | 09365214
14372096
|
| cat書誌ID | AA10731110
|
| 出版者 | Georg Thieme Verlag
|
| 巻 | 35
|
| 号 | 2
|
| 開始ページ | 235
|
| 終了ページ | 239
|
| 発行日 | 2023-10-09
|
| 備考 | 論文本文は2024-10-09以降公開予定
|
| EDB ID | |
| 出版社版DOI | |
| 出版社版URL | |
| 言語 |
eng
|
| 著者版フラグ |
その他
|
| 部局 |
薬学系
|
