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ID 116932
著者
Nakamura, Yasuyuki Shiga University of Medical Science|Yamashina Racto Clinic and Medical Examination Center
Narita, Akira Tohoku University
Sutoh, Yoichi Iwate Medical University
Imaeda, Nahomi Shigakkan University|Nagoya City University
Goto, Chiho Nagoya City University|Nagoya Bunri University
Matsui, Kenji Shiga University of Medical Science|The National Cancer Center
Takashima, Naoyuki Shiga University of Medical Science|Kindai University
Kadota, Aya Shiga University of Medical Science
Miura, Katsuyuki Shiga University of Medical Science
Nakatochi, Masahiro Nagoya University
Tamura, Takashi Nagoya University
Hishida, Asahi Nagoya University
Nakashima, Ryoko Kyushu University
Ikezaki, Hiroaki Kyushu University
Hara, Megumi Saga University
Nishida, Yuichiro Saga University
Takezaki, Toshiro Kagoshima University
Ibusuki, Rie Kagoshima University
Oze, Isao Aichi Cancer Center
Ito, Hidemi Aichi Cancer Center|Nagoya University
Kuriyama, Nagato Kyoto Prefectural University of Medicine|Shizuoka Graduate University of Public Health
Ozaki, Etsuko Kyoto Prefectural University of Medicine
Mikami, Haruo Chiba Cancer Center Research Institute
Kusakabe, Miho Chiba Cancer Center Research Institute
Nakagawa-Senda, Hiroko Nagoya City University
Suzuki, Sadao Nagoya City University
Kuriki, Kiyonori University of Shizuoka
Momozawa, Yukihide RIKEN
Kubo, Michiaki RIKEN
Takeuchi, Kenji Nagoya University
Kita, Yoshikuni Shiga University of Medical Science|Tsuruga Nursing University
Wakai, Kenji Nagoya University
キーワード
Genome-wide association study
Meat consumption
Rs671
資料タイプ
学術雑誌論文
抄録
Recent genome-wide association studies (GWAS) on the dietary habits of the Japanese population have shown that an effect rs671 allele was inversely associated with fish consumption, whereas it was directly associated with coffee consumption. Although meat is a major source of protein and fat in the diet, whether genetic factors that influence meat-eating habits in healthy populations are unknown. This study aimed to conduct a GWAS to find genetic variations that affect meat consumption in a Japanese population. We analysed GWAS data using 14 076 participants from the Japan Multi-Institutional Collaborative Cohort (J-MICC) study. We used a semi-quantitative food frequency questionnaire to estimate food intake that was validated previously. Association of the imputed variants with total meat consumption per 1000 kcal energy was performed by linear regression analysis with adjustments for age, sex, and principal component analysis components 1–10. We found that no genetic variant, including rs671, was associated with meat consumption. The previously reported single nucleotide polymorphisms that were associated with meat consumption in samples of European ancestry could not be replicated in our J-MICC data. In conclusion, significant genetic factors that affect meat consumption were not observed in a Japanese population.
掲載誌名
Journal of Nutritional Science
ISSN
20486790
出版者
Cambridge University Press|The Nutrition Society
10
開始ページ
e61
発行日
2021-10-11
権利情報
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系