口腔機能低下と身体的フレイルの臨床的関連 : 共分散構造分析を用いた横断研究
Cascade between oral function and physical frailty
檜原, 司 徳島大学大学院口腔科学教育部（口腔科学専攻）
Covariance structure analysis
Background: No report has yet examined the impact of oral hypofunction on physical frailty in relation to intra‐relationships of physical frailty assessment items. The purpose of this study was to verify the potential of a clinical cascade between oral hypofunction and physical frailty, and especially to support the hypothesis that the influence of oral hypofunction on physical frailty is greater than the intra‐relationships among elements of physical frailty, and that sex differences significantly affect these relationships.
Methods: The participants were 272 older adults (101 men and 171 women; mean age 75.1 ± 7.5 years). Maximum occlusal force (MOF) and oral dryness (OD), as indicators of oral hypofunction, and grip strength (GS) and walking speed (WS), as indicators of physical frailty, were measured. Mutual relationship of four variables was verified using covariance structure analysis.
Results: In men, three paths from MOF to WS and GS and from WS to GS were confirmed, and those from MOF to WS and from WS to GS were found to be significant (p < 0.01). In women, three paths from MOF to WS and GS and from WS to GS were also confirmed, as with the men, and those from MOF to WS and from MOF to GS were found to be significant (p < 0.01). Model adaptability was shown to be good for both men and women.
Conclusion: The results suggest our hypothesis was verified, and it is expected that the early detection of oral hypofunction, that is, MOF, may be important for assessing physical frailty, especially in women.
Journal of Oral Rehabilitation
This is the peer reviewed version of the following article: Hihara, T, Goto, T, Ichikawa, T. Assessment of potential clinical cascade between oral hypofunction and physical frailty: Covariance structure analysis in a cross-sectional study. J Oral Rehabil. 2020; 47: 61– 66, which has been published in final form at https://doi.org/10.1111/joor.12862. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
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