Yoneyama, Tatsuro Tokushima Bunri University
Iseki, Kanako Tokushima Bunri University
Noji, Masaaki Tokushima Bunri University
Imagawa, Hiroshi Tokushima Bunri University
Hashimoto, Toshihiro Tokushima Bunri University
Kawano, Sachiko Kawano-Mericlone
Baba, Masaki Meiji Pharmaceutical University
Yahagi, Tadahiro Nihon University
Matsuzaki, Keiichi Nihon University
Umeyama, Akemi Tokushima Bunri University
Cymbidium Great Flower ‘Marylaurencin’
nitric oxide production
Seven novel norcycloartane glycosides, maryloside A–G (1–7), were isolated from the leaves of Cymbidium Great Flower ‘Marylaurencin’, along with a known norcycloartane glycoside, cymbidoside (8). These structures were determined on the basis of mainly NMR experiments as well as chemical degradation and X-ray crystallographic analysis. The isolated compounds (1–6 and 8) were evaluated for the inhibitory activity on lipopolysaccharide (LPS) and interferon-γ (IFN-γ)-stimulated nitric oxide (NO) production in RAW 264.7 cells. Consequently, 1 and 3 exhibited moderate activity.
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