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ID 115830
著者
Yoneyama, Tatsuro Tokushima Bunri University
Iseki, Kanako Tokushima Bunri University
Noji, Masaaki Tokushima Bunri University
Imagawa, Hiroshi Tokushima Bunri University
Hashimoto, Toshihiro Tokushima Bunri University
Kawano, Sachiko Kawano-Mericlone
Baba, Masaki Meiji Pharmaceutical University
Yahagi, Tadahiro Nihon University
Matsuzaki, Keiichi Nihon University
Umeyama, Akemi Tokushima Bunri University
キーワード
Cymbidium Great Flower ‘Marylaurencin’
Orchidaceae
maryloside
nitric oxide production
norcycloartane glycoside
資料タイプ
学術雑誌論文
抄録
Seven novel norcycloartane glycosides, maryloside A–G (1–7), were isolated from the leaves of Cymbidium Great Flower ‘Marylaurencin’, along with a known norcycloartane glycoside, cymbidoside (8). These structures were determined on the basis of mainly NMR experiments as well as chemical degradation and X-ray crystallographic analysis. The isolated compounds (1–6 and 8) were evaluated for the inhibitory activity on lipopolysaccharide (LPS) and interferon-γ (IFN-γ)-stimulated nitric oxide (NO) production in RAW 264.7 cells. Consequently, 1 and 3 exhibited moderate activity.
掲載誌名
Molecules
ISSN
14203049
出版者
MDPI
24
13
開始ページ
2504
発行日
2019-07-09
権利情報
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
薬学系