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ID 110565
タイトルヨミ
ナゼ アレルギーセイ ビエン ワ ゾウカ シテ イルノカ
タイトル別表記
Why did the incidence of allergic rhinitis increase in Japan ?
著者
北村, 嘉章 徳島大学医学部感覚情報医学講座耳鼻咽喉科学分野 徳島大学 教育研究者総覧 KAKEN研究者をさがす
武田, 憲昭 徳島大学医学部感覚情報医学講座耳鼻咽喉科学分野 徳島大学 教育研究者総覧 KAKEN研究者をさがす
キーワード
allergic rhinitis
incidence
Japanese cedar pollen
hygiene
Western lifestyle
資料タイプ
学術雑誌論文
抄録
Allergic rhinitis (AR) is a common disease in developed countries and its incidence has increased in recent years. In Japan, although AR is rare before the 1950s, about 10-20% of population is now reported to be suffering from AR. Especially, epidemiological studies showed a remarkable increase in the incidence of Japanese cedar pollinosis within the last four decades. The reason for the high incidence of AR cannot be explained only by an increased amount of antigens, such as cedar pollen. Several hypotheses, including hygiene hypothesis, are proposed. The hygiene hypothesis that declining exposure to infections increased the incidence of AR by Th 2 predominace in the immune response is now gaining supportive evidence. Air pollution hypothesis that diesel exhaust particles enhanced IgE-mediated immune response is also proposed. A Western lifestyle is another important factor in the increase in AR. Although antihistamines and topical corticosteroids are effective therapies for the patients with AR, laser turbinectomy under endoscopy is highly effective and minimally invasive for the treatment of intractable AR. Submucosal turbinectomy with posterior-superior nasal neurectomy is indicated for the treatment of perennial AR
掲載誌名
四国医学雑誌
ISSN
00373699
cat書誌ID
AN00102041
出版者
徳島医学会
58
6
開始ページ
267
終了ページ
271
並び順
267
発行日
2002-12-25
フルテキストファイル
言語
jpn
著者版フラグ
出版社版
部局
医学系