| ID | 113348 |
| 著者 |
Komiya, Chiaki
Tokushima University
Tsukimoto, Jun
Tokushima University
Ueda, Masahiro
Tokushima University
Morisaki, Takuya
Tokushima University
|
| 資料タイプ |
学術雑誌論文
|
| 抄録 | A traceless thioester-producing protocol featuring carboxypeptidase Y-mediated hydrazinolysis of cysteinyl prolyl leucine-tagged peptides has been developed. The hydrazinolysis followed by thioesterification affords cysteinyl prolyl thioesters. Self-editing of the tag and subsequent trans-thioesterification yields peptide thioesters. The developed protocol was successfully applied to conversion of recombinant proteins to thioesters.
|
| 掲載誌名 |
Chemical Communications
|
| ISSN | 13597345
1364548X
|
| cat書誌ID | AA11071130
AA12455105
|
| 出版者 | The Royal Society of Chemistry
|
| 巻 | 55
|
| 号 | 49
|
| 開始ページ | 7029
|
| 終了ページ | 7032
|
| 発行日 | 2019-05-23
|
| 権利情報 | ©The Royal Society of Chemistry 2019
|
| EDB ID | |
| 出版社版DOI | |
| 出版社版URL | |
| フルテキストファイル | |
| 言語 |
eng
|
| 著者版フラグ |
著者版
|
| 部局 |
薬学系
|
