Claw sign predicts first-pass effect in MT
山本, 雄貴 Tokushima University 徳島大学 教育研究者総覧
山本, 伸昭 Tokushima University 徳島大学 教育研究者総覧
兼松, 康久 Tokushima University 徳島大学 教育研究者総覧 KAKEN研究者をさがす
山口, 泉 Tokushima University 徳島大学 教育研究者総覧 KAKEN研究者をさがす
石原, 学 Tokushima University 徳島大学 教育研究者総覧
宮本, 健志 Tokushima University
曽我部, 周 Tokushima University 徳島大学 教育研究者総覧
島田, 健司 Tokushima University 徳島大学 教育研究者総覧
髙木, 康志 Tokushima University 徳島大学 教育研究者総覧
和泉, 唯信 Tokushima University 徳島大学 教育研究者総覧 KAKEN研究者をさがす
Acute ischemic stroke
Background: Mechanical thrombectomy (MT) is an effective treatment for acute cerebral large vessel occlusion (LVO). Complete recanalization of vessels in a single procedure is defined as the first-pass effect (FPE) and is associated with good prognosis. In this study, angiographic clot protruding sign termed the “claw sign,” was examined as candidate preoperative imaging factor for predicting the FPE.
Methods: We retrospectively analyzed data from 91 consecutive patients treated for acute LVO in the anterior circulation by MT between January 2014 and December 2019. The claw sign was defined as a thrombus that protruded proximally by more than half of the diameter of the parent artery. Radiological findings such as claw sign, clinical and etiological features, and outcomes were compared between groups with and without successful FPE. Multivariate analysis was conducted to evaluate perioperative factors associated with FPE.
Results: FPE was achieved in 26 of 91 (28.6%) patients and the claw sign was observed in 34 of 91 (37.4%) patients. The claw sign was significantly more frequent in the successful FPE group than in the failed FPE group (53.8% vs. 30.8%; P = 0.040). After the multivariate analysis, the claw sign was the only pretreatment parameter that could predict FPE (odds ratio, 2.67; 95% confidence interval, 1.01–7.06; P = 0.047).
Conclusion: The claw sign is an angiographic imaging factor that might predict FPE after MT for anterior circulation acute ischemic stroke.
Surgical Neurology International
Surgical Neurology International|Scientific Scholar
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