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顔面神経麻痺患者の静的顔面非対称の後遺症に対する3次元スキャン解析を用いた新規評価法
著者
渕上, 輝彦 徳島大学大学院医科学教育部(医学専攻)
中村, 克彦 Tokushima University
キーワード
facial asymmetry
sequelae after facial palsy
nasolabial fold of face
three-dimensional scanning analysis
botulinum toxin
資料タイプ
学位論文
抄録
Objective: During the process of neural recovery after facial palsy, distressing sequelae of static and dynamic facial asymmetry develop in patients with facial palsy. A pronounced nasolabial fold is mainly responsible for static facial asymmetry, which leads to many psychological and social problems in patients. Objective and qualitative assessment of facial appearance is critical to determine the severity of sequelae of static facial asymmetry and whether an intervention is effective for treatment. In the present study, an attempt was made to develop three-dimensional analysis method to assess sequelae of static facial asymmetry after facial palsy.
Methods: Eight patients with sequelae of facial asymmetry after facial palsy and ten healthy volunteers were enrolled. We used three-dimensional scanning analysis with a portable non-contact optical scanner to obtain three-dimensional surface data from a patient's face and produced a three-dimensional digital model of the face. We then identified a reference plane fixed with the patient's face, and measured the depth of the nasolabial fold of the face.
Results: The nasolabial fold of the face on the affected side was significantly deeper than that on the unaffected side in patients with sequelae of static facial asymmetry after facial palsy. However, the depth of the facial nasolabial fold on the right side was not different from that on the left side in healthy volunteers. Affected-unaffected side differences in the depth of the nasolabial fold in patients with sequelae of static facial asymmetry after facial palsy were significantly larger than left-right differences in the depth of the nasolabial fold in healthy volunteers. Two weeks after treatment with botulinum toxin injection to the affected zygomaticus muscles, affected-unaffected side differences in the depth of the nasolabial fold were significantly decreased in the patients. In the patients who received botulinum toxin, the absolute values of affected-unaffected side differences in the depth of the nasolabial fold measured using the three-dimensional scanning analysis showed a significant positive correlation with the visual analog scale scores of facial asymmetry marked by independent doctors.
Conclusion: The present findings suggest that affected-unaffected side differences in the depth of the nasolabial fold of the measured using three-dimensional scanning analysis can be used as an index of sequelae of static facial asymmetry. It is also suggested that the index can evaluate whether interventions are effective for the treatment of sequelae.
掲載誌名
Auris Nasus Larynx
ISSN
03858146
cat書誌ID
AA11522116
AA00061157
出版者
Japanese Society of Otorhinolaryngology Head and Neck Surgery|Elsevier
49
5
開始ページ
755
終了ページ
761
発行日
2022-01-31
備考
内容要旨・審査要旨・論文本文の公開
本論文は,著者Teruhiko Fuchigamiの学位論文として提出され,学位審査・授与の対象となっている。
権利情報
© 2022. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
博士論文全文を含む
文科省報告番号
甲第3598号
学位記番号
甲医第1531号
学位授与年月日
2022-03-23
学位名
博士(医学)
学位授与機関
徳島大学
部局
医学系
病院