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ID 116573
タイトル別表記
A thymoma dramatically responded to PSL
著者
埴淵, 昌毅 Shikoku Central Hospital of the Mutual aid Association of Public School teachers KAKEN研究者をさがす
西條, 敦郎 Shikoku Central Hospital of the Mutual aid Association of Public School teachers KAKEN研究者をさがす
Kajimoto, Tatsuya Shikoku Central Hospital of the Mutual aid Association of Public School teachers
北川, 哲也 Shikoku Central Hospital of the Mutual aid Association of Public School teachers 徳島大学 教育研究者総覧 KAKEN研究者をさがす
キーワード
invasive thymoma
low-dose corticosteroid
single-drug therapy
資料タイプ
学術雑誌論文
抄録
A 76-year-old woman with a history of angina pectoris, hypertension and dyslipidemia was pointed out an abnormal opacity in the right hilar region on routine chest X-ray. Chest computed tomography showed masses in the anterior mediastinum with the invasion of the adjacent ascending aorta, right brachiocephalic vein and right pleura. Histologic examination led to a diagnosis of Masaoka stage IVa thymoma. Three courses of chemotherapy were given, but further tumor progression was seen. Thereafter, the patient was followed without aggressive treatments. One year after the initial diagnosis, she presented with dyspnea and right chest pain. Chest CT revealed right massive pleural effusion with pleural dissemination and much further progression of existing tumors. For the purpose of symptom palliation, a low dose (5 mg / day) of prednisolone was commenced, which unexpectedly led to marked alleviation of patient’s symptoms and dramatic decrease of pleural effusion. To the best of our knowledge, this is the first report of an invasive thymoma responded to low-dose corticosteroid. The present case suggests that corticosteroids, even at low doses, might be potentially effective for invasive thymoma after failure of surgery, chemotherapy and radiotherapy.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA11166929
出版者
Tokushima University Faculty of Medicine
68
3-4
開始ページ
396
終了ページ
399
並び順
396
発行日
2021-08
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系