アクセス数 : ?
ダウンロード数 : ?
ID 109841
タイトルヨミ
MRI ニ テキゴウ スル イリョウヨウ キンゴウキン ノ カイハツ
タイトル別表記
Research & Development of MRI Compatible Au Based Alloys for Biomedical Applications
著者
濵田, 賢一 徳島大学大学院ヘルスバイオサイエンス研究部生体材料工学分野 徳島大学 教育研究者総覧 KAKEN研究者をさがす
キーワード
MRI
金属アーチファクト
磁化率
反磁性
資料タイプ
学術雑誌論文
抄録
Metal-artifact due to volume-magnetic-susceptibility (χ) mismatch between alloy and human-tissue is one of the serious magnetic-resonance-imaging (MRI) artifacts. Alloys of susceptibility close to that of human-tissue (approximately -9 ppm) are thus required for MRI-artifact-free metal-biomedical-devices. Au-28 mass%Pt alloy is a candidate because of its χ and high corrosion resistance. However, the mechanical properties are insufficient for various types of biomedical-device. The authors found that Nb addition could improve the mechanical properties and simultaneously keep the alloy MRI-artifact-free. The authors produced an Au-8Nb-5Pt alloy wire and found that the χ value for this wire increased because of contamination during the production process. To adjust χ, the Nb content in the alloy was optimized and an Au-7Nb-5Pt alloy wire was produced. The χ value of this wire was confirmed to be close to -9 ppm. The Au-7Nb-5Pt alloy wire demonstrates higher mechanical properties than those of Au-28Pt alloy wire, and good formability. Recently, the authors are successfully producing several kinds of experimental vascular devices, such as coils for cerebral aneurysm embolization, cerebral aneurysm clips, and vascular stents. The next step of the current development is to evaluate the mechanical properties of these experimental devices, and to optimize the device designs for clinical usage.
掲載誌名
四国歯学会雑誌
ISSN
09146091
cat書誌ID
AN10050046
出版者
四国歯学会
26
2
開始ページ
29
終了ページ
34
並び順
29
発行日
2014-02-14
フルテキストファイル
言語
jpn
著者版フラグ
出版社版
部局
歯学系