| ID | 117925 |
| 著者 |
Jin, Shengjian
Tokushima University
|
| キーワード | head and neck squamous cell carcinoma
deubiquitination
ubiquitination
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| 資料タイプ |
学術雑誌論文
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| 抄録 | Ubiquitination and deubiquitination are two popular ways for the post-translational modification of proteins. These two modifications affect intracellular localization, stability, and function of target proteins. The process of deubiquitination is involved in histone modification, cell cycle regulation, cell differentiation, apoptosis, endocytosis, autophagy, and DNA repair after damage. Moreover, it is involved in the processes of carcinogenesis and cancer development. In this review, we discuss these issues in understanding deubiquitinating enzyme (DUB) function in head and neck squamous cell carcinoma (HNSCC), and their potential therapeutic strategies for HNSCC patients are also discussed.
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| 掲載誌名 |
International Journal of Molecular Sciences
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| ISSN | 14220067
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| 出版者 | MDPI
|
| 巻 | 24
|
| 号 | 1
|
| 開始ページ | 552
|
| 発行日 | 2022-12-29
|
| 権利情報 | This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
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| EDB ID | |
| 出版社版DOI | |
| 出版社版URL | |
| フルテキストファイル | |
| 言語 |
eng
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| 著者版フラグ |
出版社版
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| 部局 |
歯学系
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