直近一年間の累計
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ID 116469
タイトル別表記
CHOROIDAL STRUCTURE IN RP
著者
江川, 麻理子 Tokushima University|Japan Clinical Retina Study Group 徳島大学 教育研究者総覧 KAKEN研究者をさがす
三田村, 佳典 Tokushima University|Japan Clinical Retina Study Group 徳島大学 教育研究者総覧 KAKEN研究者をさがす
仁木, 昌徳 Tokushima University|Japan Clinical Retina Study Group 徳島大学 教育研究者総覧
Sano, Hiroki Tokushima University|Japan Clinical Retina Study Group
Miura, Gen Chiba University
Chiba, Akihiro Chiba University
Yamamoto, Shuichi Chiba University
Sonoda, Shozo Japan Clinical Retina Study Group|Kagoshima University
Sakamoto, Taiji Japan Clinical Retina Study Group|Kagoshima University
キーワード
binarization
choroidal structure
ellipsoid zone
enhanced depth imaging optical coherence tomography
retinitis pigmentosa
visual function
資料タイプ
学術雑誌論文
抄録
Purpose: To investigate the choroidal structures in the enhanced depth imaging optical coherence tomographic images in eyes with retinitis pigmentosa (RP) and to determine correlations between the choroidal structures and visual functions.
Methods: The enhanced depth imaging optical coherence tomographic images of 100 eyes with typical RP and 60 age-, sex-, and axial length–matched normal eyes were binarized using ImageJ. The cross-sectional luminal and stromal areas of the inner and outer subfoveal choroid of 1,500-µm width were measured. The inner choroid included the choriocapillaris and medium vessel layer, and the outer choroid included the larger vessel layer.
Results: In the inner choroid, the luminal area and the ratio of luminal/total choroidal area (L/C ratio) were significantly smaller in RP than in controls (P = 0.010, P < 0.001, respectively), whereas the stromal area was not significantly different (P = 0.114). The inner choroidal L/C ratio was significantly correlated with the best-corrected visual acuity, mean deviation, foveal sensitivity, width of the ellipsoid zone, and central foveal thickness in RP after adjusting for the axial length, age, and sex (all P < 0.005).
Conclusion: The significant correlations between the inner choroidal structures and the visual functions and retinal structures indicate that the choroidal structures are altered in association with the progression of RP.
掲載誌名
RETINA
ISSN
0275004X
15392864
cat書誌ID
AA10639923
AA12543461
出版者
Ophthalmic Communications Society|Wolters Kluwer
39
12
開始ページ
2399
終了ページ
2409
発行日
2019-12
権利情報
This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND)(https://creativecommons.org/licenses/by-nc-nd/4.0/), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
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フルテキストファイル
言語
eng
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出版社版
部局
医学系