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ID 111809
タイトル別表記
切迫早産に対する長期入院管理が母児の血中ビタミンD濃度に与える影響
Maternal hospitalization and vitamin D
著者
米谷, 直人 徳島大学大学院医科学教育部(医学専攻)
Nakayama, Soichiro Tokushima University
前田, 和寿 Tokushima University|2) General Perinatal Medical Center, Shikoku Medical Center for Children and Adults KAKEN研究者をさがす
キーワード
Hospitalization
Nutrition
Premature Delivery
Umbilical cord
Vitamin D
資料タイプ
学位論文
抄録
Aim: We aimed to evaluate the effect of prolonged hospitalization for threatened preterm labor on maternal and fetal vitamin D status.
Methods: This was a retrospective cohort study, spanning 4 years, including 18 women with threatened preterm labor and 36 women with normal pregnancy, who received prenatal care for a singleton pregnancy at our center. Threatened preterm labor cases were women who were admitted to our hospital after the second trimester test, for at least 28 days, during which, the third trimester test was also performed. Controls were randomly sampled from women matched for age as well as the season during which the third trimester test was performed. Serum 25-hydroxyvitamin D concentration in maternal blood was compared between the two groups at second trimester, third trimester and in the umbilical cord blood at delivery.
Results: The mean±SD of maternal serum 25-hydroxyvitamin D concentration in the threatened preterm labor group (14.0±3.0 ng/mL) was significantly lower than that in the control group (17.8±5.9 ng/mL) (p<0.01) in the third trimester, although there was no significant difference in the second trimester (p=0.30). There was a significant reduction (p<0.01) in the maternal serum 25-hydroxyvitamin D from the second to third trimester,in the threatened preterm labor group, compared to the control group (p=0.60). There was no significant difference between the two groups in umbilical cord blood 25-hydroxyvitamin D concentrations at delivery (p=0.41).
Conclusions: Prolonged hospitalization for threatened preterm labor reduced the maternal vitamin D status, but did not influence the neonatal status at delivery.
掲載誌名
The Journal of Obstetrics and Gynaecology Research
ISSN
14470756
cat書誌ID
AA11082002
出版者
Wiley
44
6
開始ページ
1042
終了ページ
1048
発行日
2018-03-23
備考
内容要旨・審査要旨・論文本文の公開
本論文は, 著者Naoto Yonetaniの学位論文として提出され, 学位審査・授与の対象となっている。
This is the peer reviewed version of the following article: Yonetani, N. , Kaji, T. , Hichijo, A. , Nakayama, S. , Maeda, K. and Irahara, M. (2018), Effect of prolonged hospitalization for threatened preterm labor on maternal and fetal vitamin D levels. J. Obstet. Gynaecol. Res., 44: 1042-1048, which has been published in final form at https://doi.org/10.1111/jog.13620. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
博士論文全文を含む
文科省報告番号
甲第3199号
学位記番号
甲医第1374号
学位授与年月日
2018-05-24
学位名
博士(医学)
学位授与機関
徳島大学
部局
病院
医学系