| ID | 109635 |
| 著者 |
Li, Xu-Hui
Tsinghua-Peking Center for Life Sciences, Tsinghua University|Zhejiang Provincial Key Laboratory of Applied Enzymology, Yangtze Delta Region Institute of Tsinghua University
Wang, Elaine Lu
Department of Legal Medicine, Kanazawa Medical University|Department of Pathology, Institute of Health Biosciences, The University of Tokushima Graduate School
Zhou, Hai-Meng
Zhejiang Provincial Key Laboratory of Applied Enzymology, Yangtze Delta Region Institute of Tsinghua University
吉本, 勝彦
Department of Medical Pharmacology, Institute of Health Biosciences, The University of Tokushima Graduate School
徳島大学 教育研究者総覧
KAKEN研究者をさがす
Qian, Zhi Rong
Department of Pathology, Institute of Health Biosciences, The University of Tokushima Graduate School|Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Harvard Medical School|Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School
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| 資料タイプ |
学術雑誌論文
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| 抄録 | MicroRNAs (miRNAs) are a class of recently identified noncoding RNAs that regulate gene expression at posttranscriptional level.
Due to the large number of genes regulated by miRNAs, miRNAs play important roles in many cellular processes. Emerging evidence indicates that miRNAs are dysregulated in pituitary adenomas, a class of intracranial neoplasms which account for 10–15% of diagnosed brain tumors. Deregulated miRNAs and their targets contribute to pituitary adenomas progression and are associated with cell cycle control, apoptosis, invasion, and pharmacological treatment of pituitary adenomas. To provide an overview of miRNAs dysregulation and functions of these miRNAs in pituitary adenoma progression, we summarize the deregulated miRNAs and their targets to shed more light on their potential as therapeutic targets and novel biomarkers. |
| 掲載誌名 |
International Journal of Endocrinology
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| ISSN | 16878337
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| 巻 | 2014
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| 開始ページ | 435171
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| 発行日 | 2014
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| 備考 | Copyright © 2014 Xu-Hui Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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| EDB ID | |
| 出版社版DOI | |
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| フルテキストファイル | |
| 言語 |
eng
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| 著者版フラグ |
出版社版
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| 部局 |
歯学系
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