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ダウンロード数 : ?
ID 84289
著者
アベ, アキコ Department of Obstetrics and Gynecology, Oe Kyodo Hospital 徳島大学 教育研究者総覧 KAKEN研究者をさがす
イカワ, ヒロシ Department of Obstetrics and Gynecology, Oe Kyodo Hospital
イカワ, サキ Department of Obstetrics and Gynecology, Oe Kyodo Hospital
キーワード
desensitization
hypersensitivity reactions
carboplatin
cisplatin
資料タイプ
学術雑誌論文
抄録
Platinum-based chemotherapy is the standard regimen for the treatment of gynecologic
cancers ; however, hypersensitivity reactions (HR) to platinum often lead to discontinuation
of this effective treatment. Here we performed a desensitization protocol
for platinum infusion in 3 patients who required platinum re-administration after developing
HR. Two patients (Case 1 and 2) were treated with the desensitization protocol
successfully without developing HR during the subsequent 3 courses. Case 3 tolerated
desensitization well for 2 courses, but in the 3rd course, she developed severe HR immediately
after the initiation of cisplatin infusion because the desensitization protocol was
unintentionally omitted. These cases show the usefulness and effectiveness of the desensitization
protocol for the continuation of platinum treatment in patients who have undergone
an extended number of treatments.
掲載誌名
The journal of medical investigation : JMI
ISSN
13431420
cat書誌ID
AA11166929
57
1-2
開始ページ
163
終了ページ
167
並び順
163
発行日
2010-02
備考
The journal of medical investigation : http://medical.med.tokushima-u.ac.jp/jmi/index.html
フルテキストファイル
言語
eng
部局
医学系