直近一年間の累計
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ID 113956
タイトル別表記
DIASTOLIC LEFT VENTRICULAR RELAXATION IN NEONATES
著者
Homma, Yukako Tokushima Prefectural Central Hospital
Terada, Tomomasa Tokushima Prefectural Central Hospital
Inoue, Miki Tokushima Prefectural Central Hospital
森, 一博 Tokushima Prefectural Central Hospital
キーワード
Diastolic wall strain
Diastolic function
Myocardial stiffness
資料タイプ
学術雑誌論文
抄録
Tissue Doppler velocity during early diastole (e’) is one of the most feasible and reproducible echocardiographic assessments to reflect active relaxation of the left ventricle. Although several reports have described the mechanisms of temporal diastolic dysfunction in the early neonatal period, factors influencing diastolic function have not been determined. The purpose of this study was to elucidate factors significantly influencing e’ in the early neonatal period.
A total of 179 consecutive normal neonates underwent echocardiographic studies performed at 0 days and 5-10 days after birth. The statistical relationships between e’ and age, body weight, mean blood pressure, heart rate, shortening fraction of the left ventricle, peak systolic motion velocity (s’), early diastolic transmitral flow velocity over annulus velocity, Tei index, and diastolic wall strain (DWS) were analyzed.
Between the 0 days and 5-10-days-after birth groups, significant differences were shown in mean blood pressure, shortening fraction of left ventricle, e’, and Tei index. Age, body weight, mean blood pressure, s’, and DWS showed significant correlations with e’. In multivariate regression analysis within these parameters, s’ (β = 0.6119, P < 0.0001) and DWS (β = 0.1216, P = 0.0321) showed positive correlations with e’.
Longitudinal systolic motion velocity and ventricular wall stiffness of the left ventricle influence diastolic relaxation in normal neonates. Age, body weight, and circumferential systolic function are not significant factors.
掲載誌名
International Heart Journal
ISSN
13493299
出版者
International Heart Journal Association
59
1
開始ページ
149
終了ページ
153
発行日
2018-01-31
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系