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ID 115062
著者
Takahashi, Wataru The University of Tokyo
Nawa, Kanabu The University of Tokyo
Yamashita, Hideomi The University of Tokyo
Imae, Toshikazu The University of Tokyo
Ogita, Mami The University of Tokyo
Okuma, Kae The University of Tokyo
Abe, Osamu The University of Tokyo
Nakagawa, Keiichi The University of Tokyo
キーワード
Pregnancy
Tongue cancer
Fetal dose
Intensity-modulated radiation therapy
Flattening filter-free
資料タイプ
学術雑誌論文
抄録
Optimizing irradiation protocols for pregnant women is challenging, because there are few cases and a dearth of fetal dosimetry data. We cared for a 36-year-old pregnant woman with tongue cancer. Prior to treatment, we compared three intensity-modulated radiation therapy (IMRT) techniques, including helical tomotherapy, volumetric arc therapy (VMAT), and flattening-filter free VMAT (FFF-VMAT) using treatment planning software. FFF-VMAT achieved the minimum fetal exposure and was selected as the optimal modality. We prescribed 66 Gy to the involved nodes, 60 Gy to the tumor bed and ipsilateral neck, and 54 Gy to the contralateral neck over 33 fractions. To confirm the out-of-field exposure per fraction, surface doses and the rectal dose were measured during FFF-VMAT delivery. Postoperative chemoradiotherapy was delivered using IMRT and a cisplatin regimen. Without any shielding, the total fetal dose was 0.03 Gy, within the limits established by the ICRP. A healthy girl was born vaginally at 37 weeks’ gestation.
掲載誌名
Clinical and Translational Radiation Oncology
ISSN
24056308
出版者
European Society for Radiotherapy and Oncology|Elsevier
20
開始ページ
9
終了ページ
12
発行日
2019-10-14
権利情報
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系