アクセス数 : ?
ダウンロード数 : ?
ID 111175
著者
Miyoshi, Takanori Tokushima Municipal Hospital
Mori, Riho Tokushima Municipal Hospital
Amano, Sachiko Tokushima Municipal Hospital
Sumitomo, Hiroyuki Tokushima Municipal Hospital
Aoyama, Mariko Tokushima Municipal Hospital
Hino, Naoki Tokushima Municipal Hospital
Wada, Daisuke Takamatsu Municipal Hospital
キーワード
Gastrointestinal stromal tumors
Synchronous lung cancer
Molecular targeting drugs
資料タイプ
学術雑誌論文
抄録
The synchronous existence of lung cancer and gastrointestinal stromal tumors (GIST) is considered to be extremely rare. To the best of our knowledge, this is the first report about the treatment of lung cancer and GIST with two kinds of molecular targeting drugs. An 83-year-old woman with a rectal GIST, which carried a c-kit mutation, and pulmonary adenocarcinoma, which exhibited an epidermal growth factor receptor (EGFR) mutation, was treated alternately with imatinib and erlotinib. Good control over both diseases was achieved for two years. The present case is not only of interest due to the rare co-occurrence of GIST and lung cancer, but also because it involved two tumors carrying different gene mutations, and both tumors were brought under control using different molecular targeting drugs.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA11166929
AA12022913
出版者
Faculty of Medicine Tokushima University
63
1-2
開始ページ
144
終了ページ
148
並び順
144
発行日
2016-02
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系