胃癌再発後の低アルブミン血症と難治性嘔吐にハロペリドールが有効で あった一症例

The patient was an 83-year-old woman who underwent laparoscopy-assisted distal gastrectomy for gastric cancer on February 25, 201X. S‐1 and UFT were performed, but metastatic liver cancer was seen on a CT scan on September 2. S‐1 was restarted on October 2６ but discontinued on January 18, 201X＋1 and best supportive care was adopted. She was hospitalized on April 15 for loss of appetite and anasarca. The patient had intractable vomiting and treatment resistance to metoclopramide and domperidone. ALB had decreased to 1．3 g/dl on April 22. A decrease in gastrointestinal motility from ascites retention was seen on a CT scan on April 25. Continuous subcutaneous infusion with haloperidol was started on April 25. The frequency of vomiting significantly decreased immediately afterward, and daily caloric intake significantly increased. Her ascites and anasarca were markedly improved on a CT scan on May 11. ALB had risen to 2．7 g/dlon June 14. Continuous subcutaneous infusion of haloperidol was effective for hypoalbuminemia and intractable vomiting after gastric cancer recurrence.