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ID 112927
タイトル別表記
肥満妊婦における血中アディポカイン値の妊娠中の推移の検討
著者
須藤, 真功 徳島大学大学院医科学教育部(医学専攻)
前田, 和寿 Tokushima University|Shikoku Medical Center for Children and Adults KAKEN研究者をさがす
Sato, Miki Tokushima University
キーワード
Adipokine
visfatin
adiponectin
pregnancy
overweight/obesity
資料タイプ
学位論文
抄録
Purpose
The purpose of this study was to investigate the differences in plasma concentrations of adipokines in pregnant women with varying body mass indices (BMIs) with every trimester.
Materials and Method
In this study, 89 pregnant women were recruited. These women were divided into lean, normal, and overweight/obese groups. Serum levels of adiponectin, resistin, leptin, and visfatin were measured in the first, second, and third trimesters.
Results
In the overweight/obese group, adiponectin, resistin, and visfatin concentrations were not significantly affected by advanced gestational age. Leptin concentrations in the third trimester were significantly higher than those in the first and second trimesters. Adiponectin concentrations in the overweight/obese group were significantly lower than those in the lean group in the first and second trimesters. Visfatin concentrations in the overweight/obese group were significantly lower than those in the normal group in the first trimester. Leptin concentrations in the overweight/obese group were significantly higher than those in the lean and normal groups in all trimesters.
Conclusion
In the first trimester, the largest differences were observed between the overweight/obese group compared to the lean and normal group. The changes in adipokines in overweight/obese groups is different from those in lean and normal groups.
掲載誌名
Gynecological Endocrinology
ISSN
09513590
14730766
cat書誌ID
AA10839977
出版者
Taylor & Francis
35
3
開始ページ
242
終了ページ
246
発行日
2018-10-16
備考
内容要旨・審査要旨・論文本文の公開
本論文は,著者Masanori Sutoの学位論文として提出され,学位審査・授与の対象となっている。
This is an Accepted Manuscript of an article published by Taylor & Francis in Gynecological Endocrinology on 16/10/2018, available online: http://www.tandfonline.com/10.1080/09513590.2018.1512572.
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
博士論文全文を含む
文科省報告番号
甲第3245号
学位記番号
甲医第1394号
学位授与年月日
2018-11-22
学位名
博士(医学)
学位授与機関
徳島大学
部局
病院
医学系