| ID | 111924 |
| 著者 |
Shimizu, Tatsuhiko
Tokushima University
Miyajima, Rin
Tokushima University
Sato, Kohei
Tokushima University
Sakamoto, Ken
Tokushima University
Naruse, Naoto
Tokushima University
Kita, Miku
Tokushima University
|
| キーワード | C-Terminal peptide thioacids
N-Sulfanylethylanilide peptide
Hydrothiolysis
Phosphate buffer
|
| 資料タイプ |
学術雑誌論文
|
| 抄録 | A facile procedure has been developed for the synthesis of C-terminal peptide thioacids under mild conditions. A series of N-sulfanylethylanilide peptides prepared using Fmoc-based solid-phase peptide synthesis were successfully converted to the corresponding thioacids via a hydrothiolysis reaction in a phosphate buffer with only trace epimerization of the C-terminal amino acid.
|
| 掲載誌名 |
Tetrahedron
|
| ISSN | 00404020
|
| cat書誌ID | AA00861787
AA11539786
|
| 出版者 | Elsevier Ltd.
|
| 巻 | 72
|
| 号 | 7
|
| 開始ページ | 992
|
| 終了ページ | 998
|
| 発行日 | 2015-12-29
|
| 権利情報 | © 2015. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
|
| EDB ID | |
| 出版社版DOI | |
| 出版社版URL | |
| フルテキストファイル | |
| 言語 |
eng
|
| 著者版フラグ |
著者版
|
| 部局 |
薬学系
|
