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ID 111560
著者
Shirai, Mutsuko The University of Tokushima
河合, 慶親 The University of Tokushima KAKEN研究者をさがす
山西, 倫太郎 The University of Tokushima KAKEN研究者をさがす
キーワード
herb extract
antidepressant activity
antioxidant
PC-12
oxidative stress
資料タイプ
学術雑誌論文
抄録
Oxidative stress is frequently mentioned in relation to the neurodegenerative diseases. This study examined the effect of three herb extracts, Hypericum perforatum, Ginkgo biloba L. and Apocynum venetum L., and their components on lipid hydroperoxide-induced oxidative stress in PC-12cells. Among them, the extract of Apocynum venetum and its components showed the remarkable inhibitory effect, indicating that this herb extract serves as a protective agent against lipid peroxidation-related oxidative stress in CNS. Oxidative stress may be associated with the progress of depression, as this extract has been proposed to be an effective antidepresant herb.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA11166929
AA12022913
出版者
Faculty of Medicine Tokushima University
52
Supplement
開始ページ
249
終了ページ
251
並び順
249
発行日
2005-11
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系