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ID 110733
著者
髙田, 信二郎 Department of Orthopedics, Institute of Health Biosciences,The University of Tokushima Graduate School
柴田, 瑩 Faculty of Pharmaceutical Sciences, Institute of Health Biosciences, The University of Tokushima Graduate School
米津, 浩 Department of Orthopedic Surgery, Shikoku Chuo Hospital
ヤマダ, トシヒデ Formulation Research Institute, Otsuka Pharmaceutical Co., Ltd.
高橋, 光彦 Department of Orthopedics, Institute of Health Biosciences,The University of Tokushima Graduate School KAKEN研究者をさがす
Abbaspour, Aziz Department of Orthopedics, Institute of Health Biosciences,The University of Tokushima Graduate School
安井, 夏生 Department of Orthopedics, Institute of Health Biosciences,The University of Tokushima Graduate School 徳島大学 教育研究者総覧 KAKEN研究者をさがす
キーワード
Fourier transform infrared spectroscopy
phosphorus-31 solid-state nuclear magnetic resonance spectroscopy
aging
bone quality
peripheral quantitative computed tomography
資料タイプ
学術雑誌論文
抄録
In this review, we focus on findings obtained with biophysic techniques, Fourier transformed infrared (FTIR) spectroscopy and phosphorus-31 solid-state nuclear magnetic resonance (31P solid-state NMR) spectroscopy, which may allow us to evaluate bone quality and to predict bone strength. FTIR measures the absorption energy that produces an increase in the vibrational or rotational energy of atoms or groups of atoms within the molecule. FTIR spectroscopy allows us to examine the relative amount of minerals and matrix content and the arrangement of apatite and organic matrix. FTIR spectroscopy should become an important tool, because the relative amount of minerals and the arrangement of apatite and organic matrix could be a measure for evaluating bone quality. 31P solid-state NMR spectroscopy is useful for evaluating the quality of bone and predicting bone strength by calculating the spine-lattice relaxation time (T1) of bone. 31Psolid-stateNMRimaging can be used to measure quantitatively the mass of hydroxyapatite. The T1 relaxation time of both bone and deficient hydroxyapatite was much longer than that of pure hydroxyapatite. T1 relaxation time is one of the promising indices of bone quality.
掲載誌名
The journal of medical investigation : JMI
ISSN
13431420
cat書誌ID
AA11166929
51
3-4
開始ページ
133
終了ページ
138
並び順
133
発行日
2004-08
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系
病院