ID 106027
著者
カスヤ, ヒデトシ Department of Neurosurgery, Tokyo Women’s Medical University
クボ, オサミ Department of Neurosurgery, Tokyo Women’s Medical University
カトウ, コウイチ Department of Neurosurgery, Tokyo Rosai Hospital
Krischek, Boris Department of Neurosurgery, University of Tübingen
キーワード
growth
histological subtype
incidental
meningioma
MIB-1
資料タイプ
学術雑誌論文
抄録
Object. With the wider use of CT and MRI, many meningiomas are discovered as incidental findings during diagnostic work-up for unrelated symptoms. The majority shows no or minimal growth. The purpose of this study was to distinguish pathological features of incidentally-found growing meningiomas by comparing incidentally-found with symptomatic meningiomas. Methods. One hundred and thirty two consecutive nonrecurrent surgically-treated meningiomas treated between 2005 and 2007 were divided into three categories : 19 incidentally-found growing meningiomas (IG), 50 incidentallyfound meningiomas (I), and 63 symptomatic (S) meningiomas. The average follow-up period for the IG meningiomas was 3.7 years. Six out of 19 patients of the IG meningiomas became symptomatic during observation. Results. There is a significant difference of the incidence of WHO grades I, II, and III between all three groups (p=0.035). The incidence of WHO grades II and III in groups IG, I, and S were 26%, 2%, and 10%, respectively. We compare MIB-1 staining index between three groups : an average was 3.8% in IG, 1.3% in I, and 2.4% in S meningiomas. Conclusions. Incidentally-found meningiomas need careful follow-up. One fourth of the meningiomas that showed signs of growing belonged to the atypical or malignant grade.
掲載誌名
The journal of medical investigation : JMI
ISSN
13431420
cat書誌ID
AA11166929
59
3-4
開始ページ
241
終了ページ
245
並び順
241
発行日
2012-08
フルテキストファイル
言語
eng
著者版フラグ
出版社版