ID 111172
タイトル別表記
大腸内視鏡検査で見逃された結腸進行腺腫と癌の形態学的特徴と部位
Advanced neoplasms after colonoscopy
著者
河村, 卓二 徳島大学大学院医科学教育部(医学専攻)
Uno, Koji Kyoto Second Red Cross Hospital
Tanaka, Kiyohito Kyoto Second Red Cross Hospital
Ueda, Yuki Kyoto Second Red Cross Hospital
Sakiyama, Naokuni Kyoto Second Red Cross Hospital
Yasuda, Kenjiro Kyoto Second Red Cross Hospital
キーワード
Colorectal cancer
interval cancer
colon polyp
laterally spreading tumor
大腸癌
大腸ポリープ
側方進展型腫瘍
資料タイプ
学位論文
抄録
This retrospective study aimed to clarify the clinical characteristics of advanced colorectal neoplasms after colonoscopy, likely to have been missed on the previous colonoscopy. We reviewed a total of 5,768 consecutive colonoscopies performed from April 2010 to September 2013 in 4,841 patients, and analyzed advanced colorectal neoplasms after colonoscopy, particularly focusing on their morphological characteristics and locations, as compared with primary lesions, defined as lesions detected in their first colonoscopy or in a subsequent colonoscopy >5 years after the previous one. Of the 5,768 examinations, 922 advanced neoplasms (including 217 cancers with≥T2) were detected, and 167 lesions (18.1%) were diagnosed within 5 years after a previous colonoscopy (post-colonoscopy advanced neoplasms). The incidence of right-sided lesions in the post-colonoscopy advanced neoplasms (48.5%, 81/167) was significantly higher than in the primary lesions (34.0%, 257/755 ; p<0.001). We excluded 217 cancers with≥T2 from the morphological analysis to characterize early-stage post-colonoscopy advanced neoplasms. The incidence of non-polypoid lesions in the post-colonoscopy advanced neoplasms (25.6%, 41/160) was significantly higher than that in the primary lesions (12.3%, 67/545 ; p<0.001). These findings suggest that extra attention should be paid to non-polypoid, right-sided advanced colorectal neoplasms during screening and surveillance colonoscopy.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA11166929
AA12022913
出版者
Faculty of Medicine Tokushima University
63
3-4
開始ページ
163
終了ページ
170
並び順
163
発行日
2016-08
備考
内容要旨・審査要旨・論文本文の公開:
内容要旨・審査要旨 : LID201606101004.pdf
論文本文 : LID201609291003.pdf
本論文は,著者Takuji Kawamuraの学位論文として提出され,学位審査・授与の対象となっている。
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
博士論文全文を含む
文科省報告番号
甲第2957号
学位記番号
甲医第1290号
学位授与年月日
2016-03-23
学位名
博士(医学)
学位授与機関
徳島大学
部局
医学系