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ID 106001
Author
Taniguchi, Kyoko Department of Psychiatry, Institute of Health Biosciences, the University of Tokushima Graduate School
Sumitani, Satsuki Department of Psychiatry, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Watanabe, Yukina Department of Psychiatry, Institute of Health Biosciences, the University of Tokushima Graduate School
Akiyama, Mai Department of Psychiatry, Institute of Health Biosciences, the University of Tokushima Graduate School
Ohmori, Tetsuro Department of Psychiatry, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
near-infrared spectroscopy (NIRS)
schizophrenia
Stroop task
hypofrontality
oxygenated hemoglobin (oxyHb)
Content Type
Journal Article
Description
The purpose of the present study was to investigate the activity of frontal lobe of patients with schizophrenia during performance of two Japanese versions of the Stroop task (kana and kanji) by measuring changes in the concentration of oxygenated hemoglobin (oxyHb) with near-infrared spectroscopy (NIRS). Fourteen schizophrenia patients and 14 age- and gender-matched healthy control subjects participated in the study after giving consent. The relative changes of concentrations of oxyHb were measured by NIRS during performance of the Stroop task. Significant Stroop effects, as measured by the number of correct responses, were observed with both the kana and the kanji versions. Analysis of NIRS data revealed that the schizophrenia patients showed reduced activation in the prefrontal cortex compared to healthy controls during performance of the kana Stroop task, and that both schizophrenia patients and healthy controls showed lack of activity in the prefrontal cortex during performance of the kanji Stroop task. The results of the present study suggest the possibility that the kana Stroop task cause a greater Stroop effect than the kanji Stroop task, and schizophrenia patients show decreased prefrontal vascular reactivity associated with the inhibition required during the performance of the kana Stroop task.
Journal Title
The journal of medical investigation : JMI
ISSN
13431420
NCID
AA11166929
Volume
59
Issue
1-2
Start Page
45
End Page
52
Sort Key
45
Published Date
2012-02
FullText File
language
eng
TextVersion
Publisher
departments
Academic Support Office for Students with Special Needs
Medical Sciences