ID 106001
著者
タニグチ, キョウコ Department of Psychiatry, Institute of Health Biosciences, the University of Tokushima Graduate School
住谷, さつき Department of Psychiatry, Institute of Health Biosciences, the University of Tokushima Graduate School 徳島大学 教育研究者総覧 KAKEN研究者をさがす
ワタナベ, ユキナ Department of Psychiatry, Institute of Health Biosciences, the University of Tokushima Graduate School
アキヤマ, マイ Department of Psychiatry, Institute of Health Biosciences, the University of Tokushima Graduate School
大森, 哲郎 Department of Psychiatry, Institute of Health Biosciences, the University of Tokushima Graduate School 徳島大学 教育研究者総覧 KAKEN研究者をさがす
キーワード
near-infrared spectroscopy (NIRS)
schizophrenia
Stroop task
hypofrontality
oxygenated hemoglobin (oxyHb)
資料タイプ
学術雑誌論文
抄録
The purpose of the present study was to investigate the activity of frontal lobe of patients with schizophrenia during performance of two Japanese versions of the Stroop task (kana and kanji) by measuring changes in the concentration of oxygenated hemoglobin (oxyHb) with near-infrared spectroscopy (NIRS). Fourteen schizophrenia patients and 14 age- and gender-matched healthy control subjects participated in the study after giving consent. The relative changes of concentrations of oxyHb were measured by NIRS during performance of the Stroop task. Significant Stroop effects, as measured by the number of correct responses, were observed with both the kana and the kanji versions. Analysis of NIRS data revealed that the schizophrenia patients showed reduced activation in the prefrontal cortex compared to healthy controls during performance of the kana Stroop task, and that both schizophrenia patients and healthy controls showed lack of activity in the prefrontal cortex during performance of the kanji Stroop task. The results of the present study suggest the possibility that the kana Stroop task cause a greater Stroop effect than the kanji Stroop task, and schizophrenia patients show decreased prefrontal vascular reactivity associated with the inhibition required during the performance of the kana Stroop task.
掲載誌名
The journal of medical investigation : JMI
ISSN
13431420
cat書誌ID
AA11166929
59
1-2
開始ページ
45
終了ページ
52
並び順
45
発行日
2012-02
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
特別修学支援室
医学系