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ID 111116
Author
Izumi, Kouji Kanazawa University
Shigehara, Kazuyoshi Kanazawa University
Nohara, Takahiro Kanazawa University
Narimoto, Kazutaka Kanazawa University
Kadono, Yoshifumi Kanazawa University
Nanjo, Shigeki Kanazawa University
Yamada, Tadaaki Kanazawa University
Ohtsubo, Koushiro Kanazawa University
Yano, Seiji Kanazawa University
Mizokami, Atsushi Kanazawa University
Keywords
advanced cancer
androgen replacement therapy
health-related quality of life
randomised controlled trial
testosterone
Content Type
Journal Article
Description
Recent studies reveal that hypogonadism with low serum androgen levels is associated with advanced cancer and induction of most cancer-related symptoms.We designed an ARTFORM study to evaluate the efficacy of androgen replacement therapy in male advanced cancer patients. The ARTFORM study is an investigatorinitiated, randomised controlled trial comparing intramuscle injection of testosterone enanthate with non-administration in male advanced cancer patients with non-curative locally advanced or metastatic lesions. Serum total and free testosterone levels are measured and patients with low testosterone level are randomised. The primary endpoint is the difference in validated health-related quality of life questionnaires at week 12. Trial registration of the ARTFORM study is assigned to University hospital Medical Information Network, Center identifier UMIN 000010939.
Journal Title
The Journal of Medical Investigation
ISSN
13496867
13431420
NCID
AA11166929
AA12022913
Publisher
Faculty of Medicine Tokushima University
Volume
64
Issue
3-4
Start Page
202
End Page
204
Sort Key
202
Published Date
2017-08
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher