ID 111116
著者
Izumi, Kouji Kanazawa University
Shigehara, Kazuyoshi Kanazawa University
Nohara, Takahiro Kanazawa University
Narimoto, Kazutaka Kanazawa University
Kadono, Yoshifumi Kanazawa University
Nanjo, Shigeki Kanazawa University
Yamada, Tadaaki Kanazawa University
Ohtsubo, Koushiro Kanazawa University
Yano, Seiji Kanazawa University
Mizokami, Atsushi Kanazawa University
キーワード
advanced cancer
androgen replacement therapy
health-related quality of life
randomised controlled trial
testosterone
資料タイプ
学術雑誌論文
抄録
Recent studies reveal that hypogonadism with low serum androgen levels is associated with advanced cancer and induction of most cancer-related symptoms.We designed an ARTFORM study to evaluate the efficacy of androgen replacement therapy in male advanced cancer patients. The ARTFORM study is an investigatorinitiated, randomised controlled trial comparing intramuscle injection of testosterone enanthate with non-administration in male advanced cancer patients with non-curative locally advanced or metastatic lesions. Serum total and free testosterone levels are measured and patients with low testosterone level are randomised. The primary endpoint is the difference in validated health-related quality of life questionnaires at week 12. Trial registration of the ARTFORM study is assigned to University hospital Medical Information Network, Center identifier UMIN 000010939.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA11166929
AA12022913
出版者
Faculty of Medicine Tokushima University
64
3-4
開始ページ
202
終了ページ
204
並び順
202
発行日
2017-08
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版