ID | 111570 |
Title Alternative | Pathological Examinations and Cancer Drugs
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Author |
Yamashita, Michiko
Tokushima Red Cross Hospital
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Keywords | cancer
pathology
formalin-fixed paraffin embedded block
FFPE
molecular targeted drugs
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Content Type |
Journal Article
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Description | The aging rate of the Tokushima prefecture is reaching globally top levels, while its cancer morbidity rate also rises. Malignant tumors can develop from almost any site in the body. Each tumor has unique, individual growth speeds. In pathological examination, a histological name is determined as ditailedly as possible to clarify the growth pattern and the treatment strategy of the tumor. Malignant tumors can be lethal, but according to one study they hardly require prolonged nursing care.
Histological diagnosis requires the following procedures : tumor identification, surgical dissection, fixing, dehydration, paraffin embedding, thin sectioning, staining, sealing, labeling and microscopic observation. Formalin-fixed paraffin embedded blocks, which help in the indication of molecular targeted drugs are generated through these processes. Since many targeted therapies block the EGFR-RAS-MAPK pathway, it is potentially one of the main mechanisms of cancer growth. Our most urgent needs include appropriate explanations about variety and “draggability” of the cancers and cultivating patients’ “will to live.” To maintain the dignity of cancer patients, we must assemble a fully developed cancer team that includes active pathologists in each local community. |
Journal Title |
Shikoku Acta Medica
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ISSN | 00373699
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NCID | AN00102041
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Publisher | 徳島医学会
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Volume | 74
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Issue | 1-2
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Start Page | 7
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End Page | 12
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Sort Key | 7
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Published Date | 2018-04-25
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FullText File | |
language |
jpn
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TextVersion |
Publisher
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