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ID 111570
タイトル別表記
Pathological Examinations and Cancer Drugs
著者
山下, 理子 徳島赤十字病院
キーワード
cancer
pathology
formalin-fixed paraffin embedded block
FFPE
molecular targeted drugs
資料タイプ
学術雑誌論文
抄録
The aging rate of the Tokushima prefecture is reaching globally top levels, while its cancer morbidity rate also rises. Malignant tumors can develop from almost any site in the body. Each tumor has unique, individual growth speeds. In pathological examination, a histological name is determined as ditailedly as possible to clarify the growth pattern and the treatment strategy of the tumor. Malignant tumors can be lethal, but according to one study they hardly require prolonged nursing care.
Histological diagnosis requires the following procedures : tumor identification, surgical dissection, fixing, dehydration, paraffin embedding, thin sectioning, staining, sealing, labeling and microscopic observation. Formalin-fixed paraffin embedded blocks, which help in the indication of molecular targeted drugs are generated through these processes. Since many targeted therapies block the EGFR-RAS-MAPK pathway, it is potentially one of the main mechanisms of cancer growth.
Our most urgent needs include appropriate explanations about variety and “draggability” of the cancers and cultivating patients’ “will to live.” To maintain the dignity of cancer patients, we must assemble a fully developed cancer team that includes active pathologists in each local community.
掲載誌名
四国医学雑誌
ISSN
00373699
cat書誌ID
AN00102041
出版者
徳島医学会
74
1-2
開始ページ
7
終了ページ
12
並び順
7
発行日
2018-04-25
フルテキストファイル
言語
jpn
著者版フラグ
出版社版