ID | 116106 |
Author |
Bando, Hiroshi
Tokushima University|Japan Low Carbohydrate Diet Promotion Association
KAKEN Search Researchers
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Keywords | Oral hypoglycemic agents (OHAs)
Sodium glucose cotransporter-2 inhibitor (SGLT-2i)
Semaglutide
Bullous pemphigoid (BP)
Hospitalization for heart failure (HHF)
Major adverse cardiovascular event (MACE)
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Content Type |
Journal Article
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Description | Current reports for oral hypoglycemic agents (OHAs) are described. As to the association of dipeptidyl peptidase-4 inhibitors (DPP-4i) and bullous pemphigoid (BP), odds ratio (OR) was vildagliptin 5.08, linagliptin 2.87, sitagliptin 1.29 (not significant). Regarding the comparative study between SGLT2i and DPP-4i, SGLT2i group showed lower hazard ratio (HR) as MACE 0.76, myocardial infarction 0.82, cardiovascular death 0.60, heart failure 0.43, all-cause mortality 0.60. Semaglutide showed reduced OR for cardiovascular death than exenatide 0.47, dulaglutide 0.46, albiglutide 0.45, lixisenatide 0.43. SGLT2i showed reduction risk of HR for MACE 0.90, hospitalization for heart failure (HHF)/cardiovascular death 0.78, renal outcomes 0.62.
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Journal Title |
Diabetes Research : Open Journal
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ISSN | 23796375
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Publisher | Openventio Publishers
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Volume | 7
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Issue | 1
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Start Page | e1
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End Page | e3
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Published Date | 2021-06-11
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Rights | This is an open-access article distributed under Creative Commons Attribution 4.0 International License (CC BY 4.0)(https://creativecommons.org/licenses/by/4.0/), which allows to copy, redistribute, remix, transform, and reproduce in any medium or format, even commercially, provided the original work is properly cited.
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DOI (Published Version) | |
URL ( Publisher's Version ) | |
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language |
eng
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TextVersion |
Publisher
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departments |
Medical Sciences
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