Latest Trend for Standards of Medical Care in Diabetes

American Diabetes Association (ADA) presents “the Standards of Medical Care in Diabetes-2022” on Jan 1, 2022. Metformin has been for long years strongly recommended as a first-line agent for type 2 diabetes mellitus (T2DM). In latest edition, metformin becomes not necessarily first-line, for atherosclerotic cardiovascular disease (ASCVD), heart failure or chronic kidney disease (CKD). For initial combination therapy, glucagon-like peptide 1 receptor agonists (GLP-1RAs) and sodium–glucose cotransporter 2 inhibitors (SGLT2i) can be applied. If eGFR is 25 mL/min/1.73m2 < or urinary albumin is 300 mg/gCr <, SGLT2i is required to prevent CKD progression and to suppress cardiovascular risk.

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