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ID 118990
Author
Bando, Hiroshi Medical Research|Tokushima University|Yoshinogawa Hospital|Japan Low Carbohydrate Diet Promotion Association KAKEN Search Researchers
Ogawa, Hiroko Yoshinogawa Hospital
Urasaki, Hirohisa Japan Low Carbohydrate Diet Promotion Association|Nankai Hospital
Urasaki, Hiroko Japan Low Carbohydrate Diet Promotion Association
Nakanishi, Miwako Yoshinogawa Hospital
Watanabe, Osami Yoshinogawa Hospital
Keywords
Imeglimin
Twymeeg
Type 2 Diabetes
75g Oral Glucose Tolerance Test
Insulinogenic Index
Japan LCD Promotion Association
Content Type
Journal Article
Description
Background: Recent pharmacological studies reveal imeglimin (Twymeeg) including dual mechanisms for stimulating insulin secretion and reducing insulin resistance.
Case Presentation: The case is a 62-year-old male with type 2 diabetes (T2D). He showed HbA1c 6.4% and started imeglimin. After 5 weeks, a 75g oral glucose tolerance test (75gOGTT) was conducted, and the biomarkers were compared with that of 6 months ago. Insulinogenic index (IGI) 0-30min was stable, but insulin secretion was increased during 30-60min and 60-120min.
Discussion: Previous studies of imeglimin revealed improved insulin secretion for GTT. Clinical progress will be followed up with detailed investigation of glucose and insulin variability.
Journal Title
Asploro Journal of Biomedical and Clinical Case Reports
ISSN
25820370
Publisher
Asploro
Volume
5
Issue
3
Start Page
113
End Page
119
Published Date
2022-08-19
Rights
This is an open-access article distributed under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Medical Sciences
University Hospital