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  2. Harada, Takeshi

Harada, Takeshi

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TGF-β-activated kinase-1 inhibitor LL-Z1640-2 reduces joint inflammation and bone destruction in mouse models of rheumatoid arthritis by inhibiting NLRP3 inflammasome, TACE, TNF-α and RANKL expression
Author Tenshin, Hirofumi/ Teramachi, Jumpei/ Ashtar, Mohannad/ Hiasa, Masahiro/ Inoue, Yusuke/ Oda, Asuka/ Tanimoto, Kotaro/ Shimizu, So/ Higa, Yoshiki/ Harada, Takeshi/ Oura, Masahiro/ Sogabe, Kimiko/ Hara, Tomoyo/ Sumitani, Ryohei/ Maruhashi, Tomoko/ Sebe, Mayu/ Tsutsumi, Rie/ Sakaue, Hiroshi/ Endo, Itsuro/ Matsumoto, Toshio/ Tanaka, Eiji/ Abe, Masahiro/
Content Type Journal Article
Journal Title Clinical & Translational Immunology
Volume 11
Issue 1
Published Date 2022-01-19
departments Oral Sciences University Hospital Medical Sciences Institute of Advanced Medical Sciences
Mechanical unloading aggravates bone destruction and tumor expansion in myeloma
Author Tanimoto, Kotaro/ Hiasa, Masahiro/ Tenshin, Hirofumi/ Teramachi, Jumpei/ Oda, Asuka/ Harada, Takeshi/ Higa, Yoshiki/ Sogabe, Kimiko/ Oura, Masahiro/ Sumitani, Ryohei/ Hara, Tomoyo/ Endo, Itsuro/ Matsumoto, Toshio/ Tanaka, Eiji/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title Haematologica
Volume 107
Issue 3
Published Date 2021-11-18
departments Oral Sciences University Hospital Medical Sciences Institute of Advanced Medical Sciences
Myeloma–Bone Interaction : A Vicious Cycle via TAK1–PIM2 Signaling
Author Harada, Takeshi/ Hiasa, Masahiro/ Teramachi, Jumpei/ Abe, Masahiro/
Content Type Journal Article
Journal Title Cancers
Volume 13
Issue 17
Published Date 2021-09-03
departments University Hospital Oral Sciences Medical Sciences
Development of a novel antioxidant based on a dimeric dihydroisocoumarin derivative
Author Nakayama, Atsushi/ Nakamura, Tenta/ Ara, Tabassum/ Fukuta, Tatsuya/ Karanjit, Sangita/ Harada, Takeshi/ Oda, Asuka/ Sato, Hideo/ Abe, Masahiro/ Kogure, Kentaro/ Namba, Kosuke/
Content Type Journal Article
Journal Title Tetrahedron Letters
Volume 74
Published Date 2021-05-10
departments Pharmaceutical Sciences University Hospital Medical Sciences
Novel antimyeloma therapeutic option with inhibition of the HDAC1-IRF4 axis and PIM kinase
Author Harada, Takeshi/ Ohguchi, Hiroto/ Oda, Asuka/ Nakao, Michiyasu/ Teramachi, Jumpei/ Hiasa, Masahiro/ Sumitani, Ryohei/ Oura, Masahiro/ Sogabe, Kimiko/ Maruhashi, Tomoko/ Takahashi, Mamiko/ Fujii, Shiro/ Nakamura, Shingen/ Miki, Hirokazu/ Kagawa, Kumiko/ Ozaki, Shuji/ Sano, Shigeki/ Hideshima, Teru/ Abe, Masahiro/
Content Type Journal Article
Journal Title Blood Advances
Volume 7
Issue 6
Published Date 2023-03-20
departments University Hospital Pharmaceutical Sciences Oral Sciences Medical Sciences
Phase angle and extracellular water-to-total body water ratio estimated by bioelectrical impedance analysis are associated with levels of hemoglobin and hematocrit in patients with diabetes
Author Hori, Taiki/ Nakamura, Shingen/ Yamagami, Hiroki/ Yasui, Saya/ Hosoki, Minae/ Hara, Tomoyo/ Mitsui, Yukari/ Masuda, Shiho/ Kurahashi, Kiyoe/ Yoshida, Sumiko/ Harada, Takeshi/ Kuroda, Akio/ Otoda, Toshiki/ Yuasa, Tomoyuki/ Endo, Itsuro/ Matsuhisa, Munehide/ Abe, Masahiro/ Aihara, Ken-ichi/
Content Type Journal Article
Journal Title Heliyon
Volume 9
Issue 4
Published Date 2023-03-21
departments Medical Sciences University Hospital Institute of Advanced Medical Sciences
The Xanthine Oxidase Inhibitor Febuxostat Suppresses Adipogenesis and Activates Nrf2
Author Higa, Yoshiki/ Hiasa, Masahiro/ Tenshin, Hirofumi/ Nakaue, Emiko/ Tanaka, Mariko/ Kim, Sooha/ Nakagawa, Motosumi/ Shimizu, So/ Tanimoto, Kotaro/ Teramachi, Jumpei/ Harada, Takeshi/ Oda, Asuka/ Oura, Masahiro/ Sogabe, Kimiko/ Hara, Tomoyo/ Sumitani, Ryohei/ Maruhashi, Tomoko/ Yamagami, Hiroki/ Endo, Itsuro/ Matsumoto, Toshio/ Tanaka, Eiji/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title Antioxidants
Volume 12
Issue 1
Published Date 2023-01-05
departments Oral Sciences University Hospital Medical Sciences Institute of Advanced Medical Sciences
Aberrant upregulation of the endogenous PP2A inhibitor CIP2A is vital for myeloma cell growth and survival
Author Shimizu, So/ Teramachi, Jumpei/ Harada, Takeshi/ Hiasa, Masahiro/ Tenshin, Hirofumi/ Oda, Asuka/ Seki, Aiko/ Inoue, Yusuke/ Tanimoto, Kotaro/ Higa, Yoshiki/ Oura, Masahiro/ Sogabe, Kimiko/ Hara, Tomoyo/ Sumitani, Ryohei/ Maruhashi, Tomoko/ Yamagami, Hiroki/ Sawa, Yoshihiko/ Endo, Itsuro/ Tsuneyama, Koichi/ Matsumoto, Toshio/ Tanaka, Eiji/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title International Journal of Myeloma
Volume 12
Issue 2
Published Date 2022
departments Oral Sciences University Hospital Medical Sciences Institute of Advanced Medical Sciences
Vascular Endothelial Function Is Associated with eGFR Slope in Female and Non-Smoking Male Individuals with Cardiovascular Risk Factors : A Pilot Study on the Predictive Value of FMD for Renal Prognosis
Author Masuda, Shiho/ Hara, Tomoyo/ Yamagami, Hiroki/ Mitsui, Yukari/ Kurahashi, Kiyoe/ Yoshida, Sumiko/ Harada, Takeshi/ Otoda, Toshiki/ Yuasa, Tomoyuki/ Nakamura, Shingen/ Kuroda, Akio/ Endo, Itsuro/ Matsumoto, Toshio/ Matsuhisa, Munehide/ Abe, Masahiro/ Aihara, Ken-ichi/
Content Type Thesis or Dissertation
Journal Title Journal of Atherosclerosis and Thrombosis
Volume 30
Issue 11
Published Date 2023
departments Medical Sciences University Hospital Institute of Advanced Medical Sciences
Therapeutic efficacy of the resorcylic acid lactone LL-Z1640-2 for adult T-cell leukaemia/lymphoma
Author Oura, Masahiro/ Harada, Takeshi/ Oda, Asuka/ Teramachi, Jumpei/ Nakayama, Atsushi/ Sumitani, Ryohei/ Inoue, Yusuke/ Maeda, Yusaku/ Sogabe, Kimiko/ Maruhashi, Tomoko/ Takahashi, Mamiko/ Fujii, Shiro/ Nakamura, Shingen/ Miki, Hirokazu/ Nakamura, Masafumi/ Hara, Tomoyo/ Yamagami, Hiroki/ Kurahashi, Kiyoe/ Endo, Itsuro/ Hasegawa, Hiroo/ Fujiwara, Hiroshi/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title eJHaem
Volume 4
Issue 3
Published Date 2023-07-27
departments University Hospital Oral Sciences Pharmaceutical Sciences Medical Sciences
Dehydroepiandrosterone Sulfate, an Adrenal Androgen, Is Inversely Associated with Prevalence of Dynapenia in Male Individuals with Type 2 Diabetes
Author Yasui, Saya/ Kaneko, Yousuke/ Yamagami, Hiroki/ Hosoki, Minae/ Hori, Taiki/ Tani, Akihiro/ Hara, Tomoyo/ Kurahashi, Kiyoe/ Harada, Takeshi/ Nakamura, Shingen/ Otoda, Toshiki/ Yuasa, Tomoyuki/ Mori, Hiroyasu/ Kuroda, Akio/ Endo, Itsuro/ Matsuhisa, Munehide/ Soeki, Takeshi/ Aihara, Ken-ichi/
Content Type Journal Article
Journal Title Metabolites
Volume 13
Issue 11
Published Date 2023-11-03
departments University Hospital Medical Sciences Institute of Advanced Medical Sciences
Cross-Sectional and Longitudinal Associations between Skin Autofluorescence and Tubular Injury Defined by Urinary Excretion of Liver-Type Fatty Acid-Binding Protein in People with Type 2 Diabetes
Author Yamagami, Hiroki/ Hara, Tomoyo/ Yasui, Saya/ Hosoki, Minae/ Hori, Taiki/ Kaneko, Yousuke/ Mitsui, Yukari/ Kurahashi, Kiyoe/ Harada, Takeshi/ Yoshida, Sumiko/ Nakamura, Shingen/ Otoda, Toshiki/ Yuasa, Tomoyuki/ Kuroda, Akio/ Endo, Itsuro/ Matsuhisa, Munehide/ Abe, Masahiro/ Aihara, Ken-ichi/
Content Type Journal Article
Journal Title Biomedicines
Volume 11
Issue 11
Published Date 2023-11-10
departments University Hospital Medical Sciences Institute of Advanced Medical Sciences
Mechanisms of preferential bone formation in myeloma bone lesions by proteasome inhibitors
Author Nakaue, Emiko/ Teramachi, Jumpei/ Tenshin, Hirofumi/ Hiasa, Masahiro/ Harada, Takeshi/ Oda, Asuka/ Inoue, Yusuke/ Shimizu, So/ Higa, Yoshiki/ Sogabe, Kimiko/ Oura, Masahiro/ Hara, Tomoyo/ Sumitani, Ryohei/ Maruhashi, Tomoko/ Yamagami, Hiroki/ Endo, Itsuro/ Tanaka, Eiji/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title International Journal of Hematology
Volume 118
Issue 1
Published Date 2023-04-11
departments Oral Sciences University Hospital Medical Sciences
Acute Myeloid Leukemia Developing with Acute Pancreatitis Mimicking Autoimmune Pancreatitis
Author Sumitani, Ryohei/ Hori, Taiki/ Murai, Jumpei/ Kawata, Shiyori/ Oura, Masahiro/ Sogabe, Kimiko/ Takahashi, Mamiko/ Harada, Takeshi/ Fujii, Shiro/ Miki, Hirokazu/ Kagawa, Kumiko/ Abe, Masahiro/ Nakamura, Shingen/
Content Type Journal Article
Journal Title Internal Medicine
Volume 60
Issue 11
Published Date 2021-06-01
departments University Hospital Medical Sciences
Unique anti-myeloma activity by thiazolidine-2,4-dione compounds with Pim inhibiting activity
Author Fujii, Shiro/ Nakamura, Shingen/ Oda, Asuka/ Miki, Hirokazu/ Tenshin, Hirofumi/ Teramachi, Jumpei/ Hiasa, Masahiro/ Bat-Erdene, Ariunzaya/ Maeda, Yusaku/ Oura, Masahiro/ Takahashi, Mamiko/ Iwasa, Masami/ Endo, Itsuro/ Yoshida, Sumiko/ Aihara, Ken-ichi/ Kurahashi, Kiyoe/ Harada, Takeshi/ Kagawa, Kumiko/ Nakao, Michiyasu/ Sano, Shigeki/ Abe, Masahiro/
Content Type Thesis or Dissertation
Journal Title British Journal of Haematology
Volume 180
Issue 2
Published Date 2018-01-12
departments University Hospital Medical Sciences Oral Sciences Pharmaceutical Sciences
Pim‐2 is a critical target for treatment of osteoclastogenesis enhanced in myeloma
Author Teramachi, Jumpei/ Hiasa, Masahiro/ Oda, Asuka/ Harada, Takeshi/ Nakamura, Shingen/ Amachi, Ryota/ Tenshin, Hirofumi/ Iwasa, Masami/ Fujii, Shiroh/ Kagawa, Kumiko/ Miki, Hirokazu/ Kurahashi, Kiyoe/ Yoshida, Sumiko/ Endo, Itsuro/ Haneji, Tatsuji/ Matsumoto, Toshio/ Abe, Masahiro/
Content Type Journal Article
Journal Title British Journal of Haematology
Volume 180
Issue 4
Published Date 2016-10-17
departments Oral Sciences University Hospital Medical Sciences Institute of Advanced Medical Sciences
A vicious cycle between acid sensing and survival signaling in myeloma cells : acid-induced epigenetic alteration
Author Amachi, Ryota/ Hiasa, Masahiro/ Teramachi, Jumpei/ Harada, Takeshi/ Oda, Asuka/ Nakamura, Shingen/ Hanson, Derek/ Watanabe, Keiichiro/ Fujii, Shiro/ Miki, Hirokazu/ Kagawa, Kumiko/ Iwasa, Masami/ Endo, Itsuro/ Kondo, Takeshi/ Yoshida, Sumiko/ Aihara, Ken-Ichi/ Kurahashi, Kiyoe/ Kuroda, Yoshiaki/ Horikawa, Hideaki/ Tanaka, Eiji/ Matsumoto, Toshio/ Abe, Masahiro/
Content Type Journal Article
Journal Title Oncotarget
Volume 7
Issue 43
Published Date 2016-09-10
departments Oral Sciences University Hospital Medical Sciences Institute of Advanced Medical Sciences
Effective impairment of myeloma cells and their progenitors by hyperthermia
Author Miki, Hirokazu/ Nakamura, Shingen/ Oda, Asuka/ Tenshin, Hirofumi/ Teramachi, Jumpei/ Hiasa, Masahiro/ Bat-Erdene, Ariunzaya/ Maeda, Yusaku/ Oura, Masahiro/ Takahashi, Mamiko/ Iwasa, Masami/ Harada, Takeshi/ Fujii, Shiro/ Kurahashi, Kiyoe/ Yoshida, Sumiko/ Kagawa, Kumiko/ Endo, Itsuro/ Aihara, Kenichi/ Ikuo, Mariko/ Itoh, Kohji/ Hayashi, Koichiro/ Nakamura, Michihiro/ Abe, Masahiro/
Content Type Journal Article
Journal Title Oncotarget
Volume 9
Issue 12
Published Date 2017-12-07
departments University Hospital Medical Sciences Oral Sciences Pharmaceutical Sciences
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